Immune Monitoring

Overview

Starting with formalin-fixed paraffin embedded tissues, the Immune Monitoring core uses the Vectra Polaris automated slide scanner and NanoString GeoMx Digital Spatial Profiler (DSP) to shed light on the molecular and cellular features of the tumor microenvironment. The Vectra Polaris performs multispectral imaging of 6 markers across 40 slides in a single run. Rapid, unambiguous phenotyping and spatial distribution of immune cells, tumor and stroma can be achieved with minimal hands-on work by the investigator. Spatial RNA sequencing from discrete individual regions of interest comprising a few hundred cells can be accomplished using the GeoMx DSP. This allows the investigator to quantify up to 800 unique transcripts.

Services

Location and Contacts

Immune Monitoring

Golding 701

 
 
 

Scientific Director
Yvonne Saenger, M.D.
718.430.2715
yvonne.saenger@einsteinmed.edu

Operations Director
Lawrence Leung, Ph.D.
lawrence.leung@einsteinmed.edu