Tissue Engineering and Cellular Reprogramming

The core provides consultation, equipment, facilities and technical support for the generation and reprogramming of a wide range of viable embryonic and neural cell types in culture and in vivo and the analysis of integrative cellular, molecular and functional properties generated from these experimental paradigms. The core houses 2 six-foot and 1 four-foot Edgegard TC Laminar Flow Hoods, 2 Steril Gard III Biosafety Hoods, P2 facility, an EMS OTS-4000 Vibratome and 12 Forma Scientific Water Jacketed Tissue Culture Incubators equipped with separate O2, CO2, N2 and additional gaseous mixture and temperature controls to support these services.

  • In vitro dissociated cell culture, slice and organotypic and whole embryo cultures
  • Embryonic stem (ES) cell experimental applications
  • Viral vector cellular manipulations for in vitro and in vivo applications
  • Human fetal cell experimentation
  • Fluorescence-activated cell sorting (FACS) for analytical and preparative experimental approaches
  • Quantitative analysis of gene expression

Related Shared Facilities
Related Shared Facilities
Center Affiliations
Center Affiliations

Rose F. Kennedy Center

Location and Contacts

Tissue Engineering and Cellular Reprogramming Kennedy Center 401
  • Mark Mehler, M.D.

  • Solen Gokhan, M.D.

  • Aldrin Molero, M.D.