Medical Scientist Training Program (MSTP)

Thesis Defense

Leti Nunez - Regulation of beta-actin mRNA by insulin-like growth factor II mRNA binding protein (IGF2BP1/ZBP1/IMP1) (Robert Singer, mentor, Anatomy & Structural Biology)

September 28 | 2:00 PM
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Featured Student

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Tsoni Peled

My favorite aspect of Einstein as a whole is the student-run free clinic, ECHO. As a first year, I worked at the front desk. As a second year, I took a position on the administrative board, which gave me invaluable experience in the issues involved in running a clinical practice. Now, while working on my thesis, I am concerned about keeping my clinical skills sharp, so I volunteer at the ECHO Free Clinic a few Saturdays a month.

 

The Medical Scientist Training Program (MSTP) at the Albert Einstein College of Medicine (Einstein) is one of the nation’s oldest. From the start, our goal has been to train a diverse group of outstanding students to become future leaders of academic medicine and medical research. Continuously funded by the National Institutes of Health since 1964, the Einstein MSTP has 499 illustrious Alumni with careers spanning the spectrum from basic science research to clinical medicine and many variations in between.

Today, the Einstein MSTP is still unique. Larger than most other MSTPs, it fosters a strong academic and social community within the college. While large enough to be an independent academic unit, the program is still small enough to provide students with the individual attention their unique careers require.

The current training program recognizes that the successful physician-scientist training is not simply medical school plus graduate training. The program integrates MSTP-specific courses with medical and graduate courses, during the first two years of preclinical course work. Integration continues in the PhD thesis years through weekly involvement in the MSTP Continuity Clinic and monthly Clinical Pathological Conferences and MSTP Career Paths seminars.

Students have outstanding publications and residency placements.

Our interview process for the class entering in 2023 will be entirely virtual. We will have an in person revisit for accepted applicants. To learn more about the Einstein community please view these two short videos: Life at Einstein and The Class of 2024. 

The Einstein MSTP encourages applications from all individuals. As stated in the College's Diversity and Inclusion Strategic Plan for Excellence, "At Einstein, we value all people and perspectives that make us unique and increase our diversity at large. Consistent with its focus on social justice, Albert Einstein College of Medicine reaffirms its commitment to recruiting, retaining and advancing individuals from historically underrepresented and marginalized minority groups in the scientific and medical professions. At the College of Medicine, this includes, (in no particular order, and is not limited to) women, individuals who are Black, Latino/Latina; Pacific Islander or indigenous Americans; individuals from new immigrant populations; individuals with both apparent and nonapparent disabilities; all sexual and gender minorities, including lesbian, gay, bisexual, asexual and queer people as well as transgender, gender-nonconforming and intersex individuals; religious minorities and individuals from economically disadvantaged backgrounds."

Four M.D.-Ph.D. students share what motivates them to pursue the long and rigorous course to become physician-scientists.  

Awards & Accomplishments

  • Eric Sosa NIH NRSA F31 Fellowship for a project entitled "Defining the gene regulatory roles of non-coding variants in the pathogenesis of autism" (Sponsor, John Greally, Genetics)
  • Tram Nguyen NIH NRSA F30 Fellowship for a project entitled "Reward Function in Adolescents with Depression and Cannabis Use" (co-Sponsors,  Vilma Gabbay and Benjamin Ely, PCI-Neuroscience & Psychiatry)
  • Gabriel Bedard NIH NRSA F30 Fellowship for a project entitled "Rational design of anti-cancer therapeutics harnessing the synthetic lethality of methionine metabolism and arginine methyltransferases" (Sponsor,  Vern Schramm, Biochemistry)
  • Matanel Yheskel NIH NRSA F31 Fellowship for a project entitled "Epigenetic and transcriptional consequences of Intellectual Disability-associated mutations in the histone lysine demethylase KDM5" (Sponsor,  Julie Secombe, Genetics)
  • Andrea Bae NIH NRSA F30 Fellowship for a project entitled "Role of brain oscillations in midbrain and forebrain networks supporting stimulus selection in the sound localization pathway of barn owls" (Sponsor,  Jose Luis Pena, Neuroscience)
  • Jacob Stauber NIH NRSA F30 Fellowship for a project entitled "Understanding stem-cell evolution dynamics of donor clonal hematopoiesis in allogeneic hematopoietic cell transplantation at a single-cell level" (co-Sponsors,  John Greally and Ulrich Steidl, Genetics and Cell Biology)
  • Ian MacArthur NIH NRSA F30 Fellowship for a project entitled "Epigenetic regulation of neural stem cell biology by Tet DNA dioxygenases" (Sponsor,  Meelad Dawlaty, Genetics)
  • Leti Nunez NIH NRSA F31 Fellowship for a project entitled "Determining the effect of RNA binding protein phosphorylation on mRNA fate" (Sponsor,  Robert Singer, Anatomy and Structural Biology)
  • Chris Nishimura NIH NRSA F30 Fellowship for a project entitled "Mechanistic Dissection and Therapeutic Targeting of B7x in Cancer" (Sponsor,  XingXing Zang, Microbiology & Immunology)
  • John "Jack" Barbaro NIH NRSA F30 Fellowship for a project entitled "Methamphetamine and Antiretroviral Therapy Impact Macrophage Functions and Macroautophagy: Implications for HIV Neuropathogenesis" (Sponsor,  Joan Berman, Pathology)
  • Ryan Graff NIH NRSA F30 Fellowship for a project entitled "Platelet PI3Kβ regulation of metastasis" (Sponsor,  Jonathan Backer and Anne Bresnick, Molecular Pharmacology)
  • Henrietta Bains NIH NRSA F31 Fellowship for a project entitled "How does mTOR sense lipid in vivo" (Sponsor,  Rajat Singh, Developmental & Molecular Biology)
  • Julio Flores NIH NRSA F31 Fellowship for a project entitled "Epigenetic regulation of stem cells and development by the DNA dioxygenase Te2" (Sponsor,  Meelad Dawlaty, Genetics)
  • Daniel Borger NIH NRSA F30 Fellowship for a project entitled "Developing a novel ex vivo platform to support hematopoietic cells and characterize the stem cell niche" (Sponsor,  Paul Frenette, Cell Biology)
  • Ryan Malonis NIH NRSA F30 Fellowship for a project entitled "Discovery & characterization of human monoclonal antibodies targeting multiple arthritogenic alphaviruses" (Sponsor, Jon Lai, Biochemistry)
  • Bianca Ulloa NIH NRSA F31 Fellowship for a project entitled "Deciphering the development of hematopoietic stem and progenitor cell self-renewal and differentiation" (Sponsor,  Teresa Bowman, Developmental & Molecular Biology)
  • Taylor Thompson NIH NRSA F31 Fellowship for a project entitled "Transcriptional Regulatory and Cell Differentiation Influences of an Endocrine Disrupting Chemical" (Sponsor, John Greally, Genetics)
  • Michelle Gulfo NIH NRSA F31 Fellowship for a project entitled "Assessing dopaminergic modulation of an associative circuit within the dentate gyrus" (Sponsor, Pablo Castillo, Neuroscience)
  • Meera Trivedi NIH NRSA F31 Fellowship for a project entitled "Characterizing Novel Regulations of Dendritic Tiling in C. elegans" (Sponsor, Hannes Buelow, Neuroscience)
  • Hayden Hatch NIH NRSA F31 Fellowship for a project entitled "Transcriptional regulation, neuronal development, and function of the mushroom body in a Drosophila model of intellectual disability" (Co-Sponsors, Julie Secombe and Nicholas Baker, Neuroscience/Genetics)

 more awards 

Publications

  • publications Pierce CA, Herold KC, Herold BC, Chou J, Randolph A, Kane B, McFarland S, Gurdasani D, Pagel C, Hotez P, Cobey S, Hensley SE. COVID-19 and children. Science. 2022 Sep 9
  • publications Núñez L, Buxbaum AR, Katz ZB, Lopez-Jones M, Nwokafor C, Czaplinski K, Pan F, Rosenberg J, Monday HR, Singer RH. Tagged actin mRNA dysregulation in IGF2BP1[Formula: see text] mice. Proc Natl Acad Sci U S A. 2022 Sep 13
  • publications Piszczatowski RT*, Schwenger E*, Sundaravel S, Stein CM, Liu Y, Stanley P, Verma A, Zheng D, Seidel RD, Almo SC, Townley RA, Bülow HE, Steidl U. A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm. J Exp Med. 2022 Nov 7
  • publications Shultis MW, Mulholland CV, Berney M. Are all antibiotic persisters created equal? Front Cell Infect Microbiol. 2022 Aug 17
  • publications Saranathan R, Asare E, Leung L, de Oliveira AP, Kaugars KE, Mulholland CV, Lukose R, Berney M, Jacobs WR Jr. Capturing Structural Variants of Herpes Simplex Virus Genome in Full Length by Oxford Nanopore Sequencing. Microbiol Spectr. 2022 Aug 30:
  • publications Weinreb JT, Bowman TV. Clinical and mechanistic insights into the roles of DDX41 in hematological malignancies. FEBS Lett. 2022 Aug 29
  • publications Bell BI, Vercellino J, Brodin NP, Velten C, Nanduri LSY, Nagesh PKB, Tanaka KE, Fang Y, Wang Y, Macedo R, English J, Schumacher MM, Duddempudi PK, Asp P, Koba W, Shajahan S, Liu L, Tomé WA, Yang WL, Kolesnick R, Guha C. Orthovoltage X-Rays Exhibit Increased Efficacy Compared with ?-Rays in Preclinical Irradiation. Cancer Res. 2022 Aug 3
  • publications Nguyen TNB, Ely BA, Pick D, Patel M, Xie H, Kim-Schulze S, Gabbay V. Clenbuterol Attenuates Immune Reaction to Lipopolysaccharide and Its Relationship to Anhedonia in Adolescents. Brain Behav Immun. 2022 Jul 29
  • publications Ren X, Li Y, Nishimura C, Zang X. Crosstalk between the B7/CD28 and EGFR pathways: Mechanisms and therapeutic opportunities. Genes Dis. 2021 Sep 20
  • publications Engel MG, Smith J, Mao K, Quipildor GF, Cui MH, Gulinello M, Branch CA, Gandy SE, Huffman DM. Evidence for preserved insulin responsiveness in the aging rat brain. Geroscience. 2022 Jul 8
  • publications Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich- Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, Wei P, Tsirigos A, Tait SWG, Kirshenbaum LA, Kitsis RN, Gavathiotis E. Modulating mitofusins to control mitochondrial function and signaling. Nat Commun. 2022 Jul 7

more publications 

Medical Scientist Training Program (MSTP)