Genomics

Overview

The Genomics Core serves the Einstein scientific community by providing a broad range of services, utilizing current and emerging nucleic acid technologies. Single-cell assays, MPS, Microarrays, real-time PCR, Sanger sequencing and assay automation are available. The Core provides a number of technologies for genotyping DNA from humans or model organisms, varying from SNP (single nucleotide polymorphism) typing to targeted sequencing for variant discovery.

Services

Single Cell Analysis

Single Cell (sc) Genomics Assays
Single Cell Western analysis
Targeted Single Cell DNA-Seq

MPS (Next Gen Sequencing) – assays include RNA-seq, ChIP-seq, ATAC-seq, MethylC-seq, HELP-tagging and MAD-seq
Gene Expression Microarrays – Affymetrix Transcriptome arrays (alt-splice detection), cost effective 3’ arrays, miRNA, fast turnaround and free data analysis software
Genotyping and Copy Number Variation (CNV) Microarrays
Single Nucleotide Polymorphism (SNP) and Mutation Analysis – Affymetrix SNP6 and CytoScan
Cytosine Methylation Analysis
Sanger Sequencing – fast service and one on one troubleshooting
Cell Line Authentication (CLA) – ensure your cell lines meet current guidelines
Microsatellite Instability Analysis (MSI)
RNA/DNA Quality Analysis – Agilent Bioanalyzer and Caliper GX
qPCR – gene expression, Taqman SNPs, 384-well, 96-well and array card formats
Liquid Handling Automation – high throughput PCR, plate replication, dilutions