Current Projects | Past Projects

Study Name Investigators and Roles Project Type
Current Projects
Investigating Dupilumab’s Effect in Asthma by genotype (IDEA) Sunit Jariwala, MD (Site PI)
Andrew Telzak, MD MSc (Site Co-I)		 Phase IV Clinical Trial
The main objective of this trial is to study if individuals ages 12 years and older, carrying the IL-4RαR576 gene variant, will have a greater response to therapy acting directly on the anti-IL-4R (via a 48-week exposure to Dupilumab).
Implementation of a Centralized Screening Unit to Increase Lung Cancer Screening and Downstage Tumors in an Urban Minority Population Dean Hosgood PhD (PI)
Andrew Telzak MD MSc (Co-I)		 Implementation Study (Multisite)
This research aims to study the extent/degree of full implementation of a centralized screening unit for lung cancer screening, to assess its impact on lung cancer screening referral rates in minoritized and low-income communities, and to determine the ‘success’ of the screening unit as measured by extent of ‘down-staging’ of lung cancer tumor stage at diagnosis.
NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation Randomized Controlled Trial (NYC CONNECT) Bruce Rapkin, PhD (mPI)
Andrew Telzak, MD MSc (Co-I)		 Randomized Controlled Trial
This study aims to assess the relative effectiveness of two evidence-based strategies to increase cancer screening rates for Breast, Colorectal and Cervical cancer, comparing enhanced usual care (with cancer screening education) with a patient navigation strategy to connect patients to cancer screening and address unmet social needs.
Penicillin Allergy De-labeling Initiative Chris Oh, MD (PI),
Andrew Telzak, MD MSc (Co-I)		 Pilot Implementation Study
This study aims to study the implementation of penicillin oral challenge protocols in the primary care setting, with the goal of delabeling penicillin allergies from patients incorrectly assigned an allergy in the Electronic Medical Record.
Redesigning Home Physical Therapy: Home Physical Therapy Regimen for Rotator Cuff Injuries Andrew Telzak, MD MSc (PI)
Olutimilehin Oyeniran MD (Co-I)		 Pilot Implementation Study
This study investigates the feasibility and effectiveness of an at-home physical therapy program for patients with rotator cuff injuries and multiple barriers to accessing traditional office-based physical therapy.
5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care (5-Cog 2.0) Joe Verghese, MBBS MS (PI)
Andrew Telzak, MD MSc (Co-I)		 Pragmatic Clinical Trial
NIA
This study uses a hybrid Type 1 effectiveness-implementation design to test the 5-cog paradigm of cognitive assessment paired with clinical decision-making support in a pragmatic, cluster randomized trial across 22 primary care sites in the Bronx and Indiana.
The goal of this study was to develop and validate a 5-minute cognitive screen coupled with a decision tree to identify and manage persons at high risk of developing dementia in multi-ethnic primary care populations with socio-economic challenges.
Pragmatic Evaluation of Events And Benefits of Lipid lowering in older Adults (PREVENTABLE) Carlos Rodriguez, MD (Site PI)
Andrew Telzak, MD MSc (Co-I)
Pragmatic Clinical Trial
(Multisite)
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study among community-dwelling older adults without cardiovascular disease (CVD) or dementia with the aim of demonstrating the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Enhancing the Community Health Worker (CHW) Model to Promote Diabetes Technology Use in Young Adults from Underrepresented Minority Groups (YA-URMs) with Type 1 Diabetes (T1D) (CATCH - T1D) Shivani Agarwal, MD (PI)
Andrew Telzak, MD MSc (Co-I)		 Randomized Clinical Trial
The objective of this study is to test the early effects and implementation of an enhanced community health worker (CHW) model (T1D-CATCH) that encourages and supports diabetes technology use in young adults from underrepresented minority groups (YA-URMs) with type 1 diabetes (T1D).
Goals for Eating and Moving (GEM) is a 12-month weight management study for patients seen by primary care teams at the Veterans Affairs and Montefiore Medical Group sites.
Study Name Investigators and Roles Project Type
Past Projects
Testing the Efficacy of a Technology- Assisted Weight Management Intervention within Patient-Centered Medical Homes: The GEM (Goals for Eating and Moving) Study Judith Wylie-Rosett, Ed.D (Site PI)
Paul Meissner, MSPH (NYC RING Liaison)		 Comparative Effectiveness
Trial (Multisite)
5-COG Battery to Improve Detection and Cognitive Impairment and Dementia Joe Verghese, MBBS MS (PI)
Asif Ansari, MD (Co-I)		 Randomized Clinical Trial
Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations (PREPARE) Diane McKee, MD MS (Site PI)
Asif Ansari MD (Co-I)
Manuja Mathur MD (Co-I)		 Comparative Effectiveness Trial (Multisite)
The goal of this study was to understand whether patient-activated reliever-triggered inhaled corticosteroid reduced asthma exacerbations in Black and Hispanic patients.
Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) Jill Crandall, MD and Diane McKee, MD
MS, (Site Co-PIs)		 Comparative Effectiveness
Trial (Multisite)
The aim of this trial was to determine which of 4 medications when added to metformin results in optimal glycemic and patient reported outcomes. (n= 5000 across 38 sites nationwide).
Acupuncture Approaches to Decrease Disparities in Outcomes of Pain Treatment (AADDOPT-2) Diane McKee, MD MS and
Ben Kligler, MD MPH (Co-PIs)		 Comparative Effectiveness
Trial
The goal of this project was to compare the effectiveness of group and individual acupuncture for primary care patients with chronic pain due to osteoarthritis, neck or back pain.
Group Acupuncture Therapy with Modified Yoga for chronic neck, low back and OA pain in safety net setting for underserved population (GAPYOGA) Diane McKee, MD MS,
Ben Kligler, MD MPH and Ray Teets,
MD (MPIs)		 Treatment Study (Multisite)
This study intended to establish the feasibility and effectiveness of acupuncture delivered in a group setting combined with modified group yoga for patients with chronic musculoskeletal neck, low back and OA pain in a safety net setting.
Childhood Asthma Perception Study (CAPS) Jonathan Feldman, PhD (PI Treatment Study - Individual
Randomization
The goal of this study was to examine the efficacy of Peak Expiratory Flow (PEF) prediction with PEF feedback versus control feedback on (1) under-perception of asthma symptoms at home and assessed in clinic (2) adherence to controller medications and (3) asthma control and emergency health care.
Developing and Evaluating an Enhanced Algorithmic Software Tool to Help Manage Asthma (ASTHMA)-Educator Mobile Application for Youth with Asthma Sunit P. Jariwala MD (PI) Single Arm Feasibility Trial
The goals of this study were (1) to enhance a previously developed ASTHMA-Educator mobile health application and (2) to evaluate the effectiveness of the enhanced ASTHMA-Educator intervention in comparison to enhanced usual care.
Bronx Ongoing Pediatric Screening (BOPS) in the Medical Home Andrew Racine, MD PhD (PI) Quality Improvement Initiative
This project sought to improve screening for pediatric preventive care, STIs, mental health, developmental assessment and newborn screening in an urban primary care network.
Blacks and Exacerbations on LABA vs. Tiotropium (BELT) Diane McKee, MD MS (Site PI)
Donald Raum, MD (Co-I)
Asif Ansari, MD (Co-I)		 Randomized Clinical Trial
(Multisite)
The goal of this study was to understand the role of genetics relative to asthma medications and treatment for Black populations.
Acupuncture to Decrease Disparities in Outcomes of Pain Treatment (ADDOPT) Diane McKee, MD MS (PI) Quasi- experimental Trial
This study assessed feasibility and acceptability of incorporating acupuncture as an adjunct to usual treatment for chronic pain in urban health centers.
5-COG Battery to Improve Detection and Cognitive Impairment and Dementia Joe Verghese, MBBS MS (PI)
Asif Ansari, MD (Co-I)		 Randomized Clinical Trial
The goal of this study was to develop and validate a 5-minute cognitive screen coupled with a decision tree to identify and manage persons at high risk of developing dementia in multi-ethnic primary care populations with socio-economic challenges.