Albert Einstein College of Medicine

Publications

  • Zheng R, Thompson K, Obeng-Gyimah E, Alessi DM, Chen J, Cheng H, McDonald TV. Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. Biochem J. 428:75-84.  2010, PMID: 20196769.   
  • McBride SMJ, Choi CH, Schoenfeld BP, Bell A, Liebelt DA, Ferreiro D, Choi RJ, Hinchey P, Kollaros M, Terlizzi A, Ferrick N, Koenigsberg E, Rudominer RL, Sumida A, Chiorean S, Siwicki KK, Nguyen HT, Fortini ME, McDonald TV, Jongens TA.  Pharmacological and genetic reversal of age dependent cognitive deficits due to decreased presenilin function. J Neuroscience   Jul 14;30(28):9510-22. 2010, PMID: 20631179. 
  • Chen J, Chen K, Sroubek J, Wu Z-Y, Bian J-S, McDonald TV. Post-transcriptional control of HERG potassium channel protein by -adrenergic receptor stimulation. Molecular Pharmacology Aug;78(2):186-97. 2010, PMID: 20463060. 
  • Ren XQ, Liu GX, Organ-Darling LE, Zheng R, Roder K, Jindal HK, Centracchio J, McDonald TV, Koren G. Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines. Am J Physiol Heart Circ Physiol. Nov;299(5):H1525-34.  2010, PMID: 20833965 
  • Choi CH, Schoenfeld BP, Bell AJ, Hinchey P, Kollaros M, Gertner MJ, Woo NH, Tranfaglia MR, Bear MF, Zukin RS, McDonald TV, Jongens TA, McBride SM.  Pharmacological reversal of synaptic plasticity deficits in the mouse model of Fragile X syndrome by group II mGluR antagonist or lithium treatment.  Brain Res. 1380:106-19.   2011,  PMID: 21078304. 
  • Sroubek J & McDonald TV.  Protein Kinase A Activity at the Endoplasmic Reticulum Surface Is Responsible for Augmentation of Human ether-a-go-go-related Gene Product (HERG). J Biol Chem. 286:21927-21936.  2011.  PMID: 21536683.  
  • Chen J, Weber M, Um SY, Walsh CA, Tang YY, & McDonald TV.  A Dual Mechanism for IKs Current Reduction by the Pathogenic Mutation KCNQ1-S277L.  Pacing & Clinical Electrophysiology. 34:1562-64. 2011. PMID: 21895724 
  • Krishnan Y, Zheng R, Walsh CA, Tang YY, McDonald TV. Partially dominant mutant channel defect corresponding with intermediate Long-QT2 phenotype.  Pacing & Clinical Electrophysiology. 35:3-16. 2012. PMID: 21951015 
  • Sroubek J, Krishnan Y, Chinai J, Buhl S, Scharff, MD & McDonald TV.  The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel. Journal of Immunological Methods. 375:215-22 2012.  PMID: 22107967 
  • Chen J, Angeletti R, McDonald TV, Xiao H.  Peptides from Cardiac Potassium Channel Reflect Interactions of Intact Proteins at Single Residue Resolution.  Analytical & Bioanalytical Chemistry 403(5):1303-9.  2012.  PMID: 22392372 
  • Krishnan Y, Li Y, Zheng R, Kanda V, McDonald TV. Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis.  Biochimica et Biophysica Acta - Molecular Cell Research 1823:1273-1284.  2012.  PMID:  22613764 
  • Erskine K, Griffith E, DeGroat N, Stolerman M, Silverstein LB, Hidayatalla N, Wasserman D, Paljevic E, Cohen L, Walsh CA, McDonald T, Marion RW, Dolan SM.   An Interdisciplinary Approach to Personalized Medicine: Case Studies from a Cardiogenetics Clinic. Personalized Medicine 10:73-80. 2013. PMID: 24496296 
  • Sroubek J, Krishnan Y, McDonald TV. Sequence and structure-specific elements of HERG mRNA regulate channel synthesis and trafficking.  FASEB J (Epub) 2013 April 22.  PMID: 23608144 
  • Schoenfeld BP, Choi RJ, Choi CH, Terlizzi AM, Hinchey P, Kollaros M, Ferrick NJ, Koenigsberg E, Ferreiro D, Leibelt DA, Siegel SJ, Bell AJ, McDonald TV, Jongens TA, McBride SM. The Drosophila DmGluRA is required for social interaction and memory. Frontiers in Pharmacology 4:64. 2013.  PMID: 23720628. 
  • Linder J, Hidayatallah N, Stolerman M, Mcdonald TV, Marion RA, Walsh CA, Dolan S. Perceptions of an Implantable Cardioverter-Defibrillator: A Qualitative Study of Families with a History of Sudden, Life-Threatening Cardiac Events, and Recommendations to Improve Care.  Einstein Journal of Biological Medicine 2014 (In Press). 
  • Silverstein LB, Hidayatallah N, Stolerman M, Cohen L, McDonald T, Walsh CA, Paljevic E, Marion RW, Wasserman D, Dolan SM.  Translating Advances In Cardiogenetics Into Effective Clinical Practice. Qualitative Health Research 2014 Aug 11. pii: 1049732314546754. [Epub ahead of print].  PMID: 25114027 
  • Wang D, Shah KR, Um SY, Eng LS, Zhou B, Lin Y, Mitchell AA, Nicaj L, Prinz M, McDonald TV, Sampson BA, Tang Y. Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths. Forensic Sci Int. 2014 Apr;237:90-9. PMID: 24631775 
  • Erskine K, Hidayatalla N, Silverstein LB, Walsh CA, McDonald TV, Cohen L, Marion RW, Dolan SM.  Motivation to Pursue Genetic Testing in Individuals with a Personal or Family History of Cardiac Events or Sudden Cardiac Death. Journal of Genetic Counseling 2014 Oct;23(5):849-59.  PMID: 24664857 
  • Hidayatallah N, Silverstein LB, Stolerman M, McDonald T, Walsh CA, Paljevic E, Cohen LL, Marion RW, Wasserman D, Hreyo S, Dolan SM. Psychological stress associated with cardiogenetic conditions. Personalized Medicine (In Press) 2014 
  • Choi C, Schoenfeld B, Weisz E, Bell A, Chambers D, Hinchey J, Choi R, Hinchey P, Kallaros M, Gertner M, Ferrick N, Terlizzi A, Yohn N, Woo N, Tranfaglia M, Louneva N, Arnold S, Siegel S, Bolduc F, McDonald T, Jongens T, McBride S.  PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of Fragile X syndrome.  Journal of Neuroscience  35:396-408. 2015 PMID: 25568131 
  • Osterbur M, Zheng R, Marion RW, Walsh CA & McDonald TV. An interdomain hERG mutation produces an intermediate Long QT phenotype.  Human Mutation (In Press) 2015. 
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