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Lijie Shi
Email: lshi@mail.einsteinmed.org
LinkedIn
Education:
Ph.D Candidate, Albert Einstein College
of Medicine
MS, Shandong University, China
Research interest:
One allele of Crkl gene is deleted in most of 22q11.2
deletion syndrome patients, and up to 62% of patients in our cohort have
congenital heart defects. Crkl gene
encodes an adaptor protein involving in many signal pathways in cells. Mice Crkl null embryos exhibit various
aspects of heart defects and die around embryonic 16.5 days. My projects mainly
focus on the study of the tissue specific function of Crkl in mouse heart development. We use
mouse as research model aiming to find out the molecular mechanism of Crkl function in mouse, also in human
early heart developments.
Previous publications:
- Shuai Wang,
An-Jing Chen, Lijie Shi
(co-first author), Xiaofan
Zhao, Jinxing Wang. TRBP and eIF6 homologue in Marsupenaeus japonicus
play crucial roles in antiviral response. PloS ONE. 2012;7(1):e30057.
Shuai Wang,
Lijie Shi
(co-first author), Ning Liu, An-Jing Chen, Xiaofan
Zhao, Jinxing Wang. Involvement of Fenneropenaeus chinensis
Cathepsin
C in antiviral immunity. Fish & Shellfish Immunology.
2012;33(4):821-828.
- Shi
Xiuzhen, Lijie Shi
(co-first author), Zhao Yanran,
Zhao Xiaofan,
Wang Jinxing. β-Thymosins
participate in antiviral immunity of red swamp crayfish (Procambarus
clarkii). Dev Comp Immunol.
2015 Aug;51(2):213-225.
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