Wang, Y.; Morisseau C.; Takamura, A.; Wan, D.; Li D.; Sidoli S.; Yang J.; Wolan, D.W.#; Hammock, B.D. #; Kitamura, S.# (corresponding). A PROTAC that induces lysosomal degradation of the cytosolic target protein. ACS Chemical Biology 2023. doi: 10.1021/acschembio.3c00017
Garnar-Wortzel, L.*, Bishop, T.*, Kitamura, S.* (co-first author); Milosevich, N.; Asiaban, J.; Zhang, X.; Zheng, Q.; Chen, E.; Ramos, A.; Ackerman, C.; Hampton, E.; Chatterjee, A.; Young, T.; Hull, M.; Sharpless K.B.; Cravatt, B.; Wolan, D. W. ; Erb, M., Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia. ACS Central Science 2021. doi: 10.1021/acscentsci.0c01550
Woehl, J.L.*; Kitamura, S.* (co-first author); Dillon, N.; Han, Z.; Edgar, L.J.; Nizet, V.; Wolan, D.W. An irreversible inhibitor to probe the role of Streptococcus pyogenes cysteine protease SpeB in evasion of host complement defenses. ACS Chemical Biology 2020, doi: 10.1021/acschembio.0c00191.
Kitamura, S.; Zheng, Q.; Woehl, J. L.; Solania, A.; Chen, E.; Dillon, N.; Hull M.; Kotaniguchi, M.; Kitamura, S.; Nizet, V.; Sharpless, K. B.; Wolan, D.W., (2020): SuFEx-Enabled High-Throughput Medicinal Chemistry. Journal of the American Chemical Society 2020, doi: 10.1021/jacs.9b13652.
Yao Y.; Kadam R.U.; Lee C.-C.D.; Woehl J.L.; Wu N.C.; Zhu X.; Kitamura S.; Wilson I.A.; Wolan D.W., An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proceedings of the National Academy of Sciences 2020, doi.org/10.1073/pnas.200689311.
Kok, B. P.; Ghimire, S.; Kim, W.; Chatterjee, S.; Johns, T.; Kitamura, S.; Eberhardt, J.; Ogasawara, D.; Xu, J.; Sukiasyan, A.; Kim, S. M.; Godio, C.; Bittencourt, J. M.; Cameron, M.; Galmozzi, A.; Forli, S.; Wolan, D. W.; Cravatt, B. ; Boger, D. L.; Saez, E., Discovery of small-molecule enzyme activators by activity-based protein profiling. Nature Chemical Biology 2020, doi: 10.1038/s41589-020-0555-4.
Bess, E. N.; Bisanz, J. E.; Yarza, F.; Bustion, A.; Rich, B. E.; Li, X.; Kitamura, S.; Waligurski, E.; Ang, Q. Y.; Alba, D. L.; Spanogiannopoulos, P.; Nayfach, S.; Koliwad, S. K.; Wolan, D. W.; Franke, A. A.; Turnbaugh, P. J., Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria. Nature Microbiology 2020, doi.org/10.1038/s41564-019-0596-1.
Kitamura, S.; Owensby, A.; Wall, D.; Wolan, D. W.; Lipoprotein signal peptidase inhibitors with antibiotic properties identified through design of a robust in vitro HT platform. Cell Chemical Biology 2017, doi: 10.1016/j.chembiol.2017.12.011.
Kitamura, S.; Hvorecny, KL.; Niu, J.; Hammock, BD.; Madden, DR.; Morisseau, C.; Rational design of potent and selective inhibitors of an epoxide hydrolase virulence factor from Pseudomonas aeruginosa. Journal of Medicinal Chemistry 2016, doi.org/10.1021/acs.jmedchem.6b00173.