For an up to date list: https://www.ncbi.nlm.nih.gov/myncbi/julie.secombe.1/bibliography/public/
Recent publications
Rogers, M.F., Marshalll, O.J., and J. Secombe (2023) KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila. BioRxiv https://www.biorxiv.org/content/10.1101/2023.05.23.541787v1
Schneider, B.K., Sun, S., Lee, M., Li, W., Skvir, N., Neretti, N., Vijg, J., and J. Secombe (2023) Expression of transposons contributes to aging in Drosophila. Genetics, DOI: 10.1093/genetics/iyad073
Yheskel, M., Sidoli, S., and J. Secombe (2023). Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5. Epigenetics & Chromatin 16(8) doi.org/10.1186/s13072-023-00481-y. PMID:36803422.
Hatch, H.A.M., O’Neill, M.H., Marion, R.W., Secombe, J.#., and L.H. Shulman# (2021) Caregiver-reported characteristics of children diagnosed with pathogenic variants in KDM5C. American Journal of Medical Genetics - Part A, doi:10.1002/amjg.a.62381 PMID:34089235
Hatch, H.A.M., Belalcazar H.M., Marshall O.J., and Secombe J (2021) A KDM5-Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation. eLife doi.org/10.7554/elife.63886 PMID: 33729157
Belalcazar, H.M., Hendricks, E.L., Zamurrad, S., Liebl, F.L.W., and Secombe J (2021) The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction. Cell Reports, 34(7):108753. DOI:10.1016/j.celrep.2021.108753. PMID:33596422
Drelon, D., Rogers, M.F., H. M. Belalcazar, and J. Secombe (2019) The histone demethylase KDM5 controls developmental timing by promoting prothoracic gland endocycles. Development, 146(24)pii:dev182568. PMID:31862793
Chen, K., Luan, X., Liu, Q., Wang, J., ChangX., Snijders A. M., Mao J-H., Secombe J., Dan Z, Chen J-H., Wang Z., Dong X., Qiu C., Chang X., Zhang D., Celniker S. E., and Xingyin Liu (2019) Drosophila KDM5 regulates social behavior through immune control and gut microbiota maintenance. Cell Host & Microbe25, 1-16. PMID:30902578
Drelon, C., Belalcazar, H.M., and J. Secombe (2018) The histone demethylase KDM5 is essential for larval growth in Drosophila. Genetics 209(3):773-787. PMID:29764901
Zamurrad, S., Hatch, H.A.M., Drelon, C., Belalcazar, H.M, and J.Secombe (2018) A Drosophilamodel of intellectual disability caused by mutations in the histone demethylase KDM5. Cell Reports 22, 2359-2369. PMCID:PMC5854480.
Navarro-Costa, P., McCarthy, A., Prudencio, P., Greer, C., Guilgur, L.G., Becker, J., Secombe, J., Rangan, P and R. Martinho (2016) Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat. Comms. 10;7:12331.
Liu, X., and J. Secombe (2015) The histone demethylase KDM5 activates gene expression by recognizign chromatin context through its PHD reader motif. Cell Reports, 13:2219-2231.
Liu, X., Greer, C., and J. Secombe (2014) KDM5 interacts with Foxo to modulate cellular levels of oxidative stress. PLos Genetics 10(10): e1004676