![Life and Death of mRNA]()
The National Institute of General Medical Sciences has awarded Robert Singer, Ph.D., a four-year, $1.3 million renewal grant to study regulatory DNA sequences and factors that regulate messenger RNA (mRNA). Discovering how cells regulate mRNA and proteins involved in cell growth and division may lead to insights into cancer, birth defects and susceptibility to infections. Dr. Singer’s team has discovered information within the promoter (the initiating sequence of a gene) that determines the fate of mRNA. Using innovative tools including fluorescently labeled mRNA and imaging of living cells, the researchers will study the steps involved in the life of mRNA and the factors coordinating those steps. Dr. Singer is professor and co-chair of anatomy and structural biology, as well as co-director of the Gruss-Lipper Biophotonics Center and of the Integrated Imaging Program. He also is professor in the Dominick P. Purpura Department of Neuroscience and of cell biology and the Harold and Muriel Block Chair in Anatomy & Structural Biology.
Posted on: Thursday, February 11, 2016