![Learning How Dendrites are Formed]()
Hannes Buelow, Ph.D., has received a five-year, $1.8 million National Institutes of Health grant to study molecular mechanisms involved in dendrite development. Dendrites are the structures in neurons that receive information from other neurons. Defects in dendrite shape are found in numerous pathological conditions such as certain forms of mental retardation and autism spectrum disorders. In studies involving the roundworm Caenorhabditis elegans, Dr. Buelow has found a new molecular pathway, the ‘menorin’ pathway, which orchestrates development of the worm’s menorah-shaped PVD dendrites. He and his group will use genetic and biochemical methods to identify signaling pathways that shape dendrite development. Dr. Buelow is associate professor of genetics and in the Dominick P. Purpura Department of Neuroscience. (1R01NS096672-01A1)
Posted on: Monday, September 12, 2016