Current Members: Yingjie Jhao

Yingjie Zhao, Ph.D.

Email: yingjie.zhao@einsteinmed.org 

Education: 

B.S., Biologi, Lanzhou University, Gansu Province, China

Ph.D., Genetics, School of Life Sciences, Fudan University, Shanghai, China

Research interest:

Yingjie’s work focuses on the etiology and heterogeneity of cardiac congenital heart defects among 22q22.1 deletion syndrome populations. She has great interests on large-scale data analysis and mining including genome wide association study, whole exome sequencing and whole genome sequencing. 

Previous publications:

1. Zhao Y*, Chen G*, Zhao Y, Song X, Chen H, Mao Y and Lu D. Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population. International Journal of Cancer. 2012; 131(7):1569-1576. 
2. Zhao Y*, Chen G*, Yu H, Hu L, Bian Y, Yun D, Chen J, Chen H, Mao Y, Lu D. Development of Risk Prediction Models for Glioma Based on Genome-Wide Association Study Findings and Comprehensive Evaluation of Predictive Performances. Oncotarget. 2016; Epub ahead of print.  
3. Zhao Y*, Yun D*, Zou X, Jiang T, Li G, Yun D, Chen G, Hu L, Bian Y, Chen J, Xu J, Mao Y, Chen H and Lu D. Whole Exome-Wide Association Study Identifies a Missense Variant in SLC2A4RG Associated with Glioblastoma Risk. American Journal of Cancer Research. Accepted 
4. Zhao Y, Zou X, Jiang T, Li G, Yun D, Chen G, Hu L, Bian Y, Chen J, Xu J, Mao Y, Chen H and Lu D. Whole-exome array analysis of glioblastoma susceptibility in a Chinese population. Submitted to Carcinogeneises, Under review 
5. Zhao Y, Yun D, Zou X, Chen G, Bian Y, Yun D, Hu L, Bian Y, Genome wide survival analysis of glioblastoma. In drafting 
6. Song X, Zhou K, Zhao Y, Huai C, Zhao Y, Yu H, Chen Y, Chen G, Chen H, Fan W, Mao Y and Lu D. Fine mapping analysis of a region of 20q13.33 identified five independent susceptibility loci for glioma in a Chinese Han population. Carcinogenesis. 2012; 33(5):1065-1071.
7. Fan S*, Zhao Y*, Li X, Du Y, Wang J, Song X, Zhou F, Chen H, Chen G, Zhao Y, Mao Y and Lan Q. Genetic variants in SLC7A7 are associated with risk of glioma in a Chinese population. Experimental biology and medicine. 2013; 238(9):1075-1081.
8. Wu Y, Yun D, Zhao Y, Wang Y, Sun R, Yan Q, Zhang S, Lu M, Zhang Z, Lu D. Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer. Oncotarget. 2016; Accepted 
9. Chen H, Sun B, Zhao Y, Song X, Fan W, Zhou K, Zhou L, Mao Y and Lu D. Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma. PloS one. 2012; 7(12): e52864.
10. Meng D, Chen Y, Zhao Y, Wang J, Yun D, Yang S, Chen J, Chen H and Lu D. Expression and prognostic significance of TCTN1 in human glioblastoma. Journal of translational medicine. 2014; 12:288.
11. Hu D, Zhang S, Zhao Y, Wang S, Wang Q, Song X, Lu D, Mao Y and Chen H. Association of genetic variants in the retinoblastoma binding protein 6 gene with the risk of glioma: a case-control study in a Chinese Han population. Journal of neurosurgery. 2014; 121(5):1209-1218.
12. Fan W, Zhou K, Zhao Y, Wu W, Chen H, Jin L, Chen G, Shi J, Wei Q, Zhang T, Du G, Mao Y, Lu D and Zhou L. Possible association between genetic variants in the H2AFX promoter region and risk of adult glioma in a Chinese Han population. Journal of neuro-oncology. 2011; 105(2):211-218.
13. Chen H, Wang W, Zhao Y, Song X, Fan W, Zhou K, Chen G, Zhao Y, Mao Y and Lu D. Association between genetic variations of vascular endothelial growth factor receptor 2 and glioma in the Chinese Han population. J Mol Neurosci. 2012; 47(3):448-57.
14. Meng D, Chen Y, Yun D, Zhao Y, Wang J, Xu T, Li X, Wang Y, Yuan L, Sun R, Song X, Huai C, Hu L, Yang S, Min T, Chen J, et al. High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma. Oncotarget. 2015; 6(7):4901-4919.
15. Li X, Qu L, Zhong Y, Zhao Y, Chen H and Lu D. Association between promoter polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis. J Cancer Res Clin Oncol. 2013;139(9):1433-47.
16. Fan W, Zhou K, Hu D, Song X, Zhao Y, Chen H, Wei Q, Chen G, Shi J, Du G, Mao Y, Lu D and Zhou L. Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population. Molecular carcinogenesis. 2012; 51 Suppl 1: E1-10.
17. Chen Y, Meng D, Wang H, Sun R, Wang D, Wang S, Fan J, Zhao Y, Wang J, Yang S, Huai C, Song X, Qin R, Xu T, Yun D, Hu L, et al. VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells. Neuro-oncology. 2015; 17(3):407-418.