Bernice Morrow Lab

Current Members: Christopher De Bono

Christopher De Bono   

Christopher De Bono



B.S in Cell Biology, Aix-Marseille University, France 

M.S in Development and Immunology, Aix-Marseille University, France  

Ph.D in Developmental Biology, Aix-Marseille University, France 

Research interest:

Christopher’s projects in the area of single cell RNA-sequencing aim to investigate the roles of Tbx1, the major candidate gene for 22q11.2 deletion syndrome, during early embryonic development. Specifically, his projects focus on the understanding of cell autonomous roles of Tbx1 in the endoderm and ectoderm of embryos and of non-autonomous functions of Tbx1 on adjacent neural crest cells. 

Previous publications:

  1. De Bono C, Thellier C, Bertrand N, Sturny R, Jullian E, Cortes C, Stefanovic S, Zaffran S, Theveniau-Ruissy M, Kelly RG: T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field. Hum Mol Genet 2018, 27(21):3747-3760.  

  2. Cortes C, Francou A, De Bono C, Kelly RG: Epithelial Properties of the Second Heart Field. Circ Res 2018, 122(1):142-154.  

  3. De Bono C, Theveniau-Ruissy M and Kelly RG. Cardiac Fields and myocardial cell lineages. In “The ESC Textbook of Cardiovascular Development”. Oxford University Press, 2018  

  4. Francou A, De Bono C, Kelly RG: Epithelial tension in the second heart field promotes mouse heart tube elongation. Nat Commun 2017, 8:14770.   

  5. Rana MS, Theveniau-Ruissy M, De Bono C, Mesbah K, Francou A, Rammah M, Dominguez JN, Roux M, Laforest B, Anderson RH, Mohun TJ, Zaffran S, Christoffels VM, Kelly RG: Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart. Circ Res 2014, 115(9):790-799.  


Contact Us

Dr. Bernice Morrow 

1301 Morris Park Avenue
Price 408
Bronx, NY 10461

Tel: 718.678.1122

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