For a complete list see: https://scholar.google.com/citations?user=y2BA7ToAAAAJ&hl=en
† corresponding author | * contributed equally
Veling MT*, Nguyen DT*, Thadani NN, Oster ME, Rollins NJ, Brock KP, Bethel NP, Lim S, Baker D, Way JC, Marks DS, Chang RL†, Silver PA†. Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells. ACS Synth Biol. 2022 Mar 18;11(3):1292-1302. doi: https://doi.org/10.1021/acssynbio.1c00572
Chang RL†, Stanley JA, Robinson MC, Sher JW, Li Z, Chan YA, Omdahl AR, Wattiez R, Godzik A, Matallana-Surget S†. Protein structure, amino acid composition and sequence determine proteome vulnerability to oxidation-induced damage. EMBO J. 2020, Oct 19; e104523. doi: https://doi.org/10.15252/embj.2020104523
Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM†, Lewis NE†. Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow. Proc Natl Acad Sci U S A. 2018, Oct 23; 115(43):11096-11101. doi: https://doi.org/10.1073/pnas.1811971115
Chang RL, Xie L, Bourne PE, Palsson B؆. Antibacterial mechanisms identified through structural systems pharmacology. BMC Syst Biol. 2013, Oct 10; 7:102. doi: https://doi.org/10.1186/1752-0509-7-102
Chang RL, Andrews K, Kim D, Li Z, Godzik A, Palsson B؆. Structural systems biology evaluation of metabolic thermotolerance in Escherichia coli. Science. 2013, Jun 7; 340(6137):1220-1223. doi: https://doi.org/10.1126/science.1234012
Chang RL, Ghamsari L, Manichaikul A, Hom EF, Balaji S, Fu W, Shen Y, Hao T, Palsson BØ, Salehi-Ashtiani K†, Papin JA†. Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism. Mol Syst Biol. 2011, Aug 2; 7:518. doi: https://doi.org/10.1038/msb.2011.52
Chang RL, Xie L, Xie L, Bourne PE, Palsson B؆. Drug off-target effects predicted using structural analysis in the context of a metabolic network model. PLoS Comput Biol. 2010, Sep 23; 6(9):e1000938. doi: https://doi.org/10.1371/journal.pcbi.1000938