Kim, J., Sun, C., Tran, A.D., Chin, P.J., Ruiz, P.D., Wang, K., Gibbons, R.J., Gamble, M.J., Liu, Y. and Oberdeorffer, P. (2019) "The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening." Nat. Struct. Mol. Biol. 26:213-219.
Ruiz, P.D. and Gamble, M.J. (2018) "MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20." Nat. Commun. 9:5143.
Hodge, D.Q., Cui, J., Gamble, M.J. and Guo, W. (2018) "Histone variant macroH2A1 plays an isoform-specific role in suppressing epithelial-mesenchynmal transition." Sci. Rep. 8:841.
Chen, H., Ruiz, P.D., McKimpson, W.M., Novikov, L., Kitsis, R.N. and Gamble, M.J. (2015) “MacroH2A1 and ATM play opposing roles in paracrine senescence and the senescence-associated secretory phenotype.†Mol. Cell 59:719-31.
Chen, H., Ruiz, P.D., Novikov, L., Casill, A.D., Park, J.W. and Gamble, M.J. (2014) “MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation.†Nat. Struct. Mol. Biol. 21:981-9.
Hussey, K.M., Chen, H., Yang, C., Park, E., Hah, N., Erdjument-Bromage, H., Tempst, P., Gamble, M.J.*, Kraus, W.L.* (2014) “The histone variant macroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.†Mol Cell Biol. 34:2437-49.
Gamble, M.J. (2013) Expanding the functional repertoire of macrodomains. Nat Struct Mol Biol 20:407-8
Zhang, T., Berrocal, J.G., Yao, J., DuMond, M.E., Krishnakumar, R., Ruhl, D.D., Gamble, M.J., and Kraus, W.L. (2012) “Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.†J. Biol. Chem. 287:12405-16.
Novikov, L., Klerman, H., Jalloh, A.S., and Gamble, M.J. (2011) “QKI-mediated alternative splicing of the histone variant macroH2A1 regulates cancer cell proliferation.†Mol Cell Biol. 31:4244-4255
Zhang, X., Gamble M.J., Stadler, S., Cherrington, B.D., Causey, C.P., Thompson, P.R., Robertson, M.S., Kraus, W.L., Coonrod, S.A. (2011) “Genome-wide analysis reveals PADI4 Cooperates with ELK-1 to activate c-Fos expression in Breast Cancer Cells.†PLoS Genetics. 7:e1002112.
Gamble, M.J. and Kraus, W.L. (2010) “Multiple facets of the unique histone variant macroH2A: from genomics to cell biology.†Cell Cycle 9:2568-2574.
Gamble, M.J., Frizzell, K.M., Yang, C., Krishnakumar, R., Kraus, W.L. (2010) “The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing.†Genes and Development 24:21-32
Frizzell, K.M., Gamble, M.J., Zhang, T., Berrocal, J.G., Zhang, T., Krishnakumar, R., Cen, Y., Sauve, A.A., and Kraus, W.L. (2009) "Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells." Molecular and Cellular Biology. 284:33926-28
Zhang, T., Berrocal, J.G., Frizzell, K.M., Gamble, M.J., Dumond, M.E., Krishnakumar, R., Yang, T., Sauve, A.A., Kraus, W.L. (2009) “Enzymes in the NAD+ Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters.†J. Biol Chem. 284:20408-17
Krishnakumar, R.*, Gamble, M.J.*,Frizzell, K.M., Berrocal, J.G., Kininis, M., Kraus, W.L. (2008) Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes. Science 319:819-21 (* equal contribution)
Gamble, M.J. and Fisher R.P. (2007) SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery. Nat Struct Mol Biol. 14;548-55
Gamble, M.J. and Kraus W.L. (2007) Visualizing the histone code on LSD1. Cell 128:433-4
Larochelle, S., Batliner, J., Gamble, M.J., Barboza, N.M., Kraybill, B.C., Blethrow, J.D., Shokat, K.M., Fisher, R.P.(2006) Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nat Struct Mol Biol 13:55-62
Gamble, M.J., Erdjument-Bromage, H., Tempst, P., Freedman, L.P., Fisher, R.P. (2005) The histone chaperone, TAF-I/SET, is required for activated transcription in vitro of chromatin templates. Mol Cell Biol 25:797-807
Gamble, M.J., Freedman, L.P. (2002) A coactivator code for transcription. Trends Biochem Sci 27: 165-7.
Rachez, C., Gamble, M.J., Chang, C.P., Atkins, G.B., Lazar, M.A. Freedman, L.P. (2000) The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes. Mol Cell Biol 20:2718-26.
Rachez, C., Lemon, BD., Suldan, Z., Bromleigh, V., Gamble, M., Naar, A.M., Erdjument-Bromage, H., Tempst, P., and Freedman, L.P. (1999) Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature 398:824-8.