Cai D, Khor S. "Hypothalamic Microinflammation" Paradigm in Aging and Metabolic Diseases. Cell Metabolism. 2019 Jul 2;30(1):19-35.
Zhang Y, Kim M, Jia B, Yan J, Hertz J, Han C, Cai D. Hypothalamic stem cells control ageing speed partly through exosomal miRNAs. Nature (article), 2017 Aug 3; 548(7665):52-57.
(Highlighted via Nature News in Nature 547: 389, 2017, highlighted via Science News in Science July 26, 2017, highlighted in Nature Reviews Neuroscience 2017)
Zhang YL, Reichel JM, Han C, Zuniga-Hertz JP, Cai D. Astrocytic process plasticity and IKK/NF-kB in central control of blood glucose, blood pressure and body weight. Cell Metabolism. 2017, May 2; 25(5); 1091-1102.
(Highlighted in a preview in Cell Metabolism 2017; 25(5):995-996)
Zhang YM, Liu G, Yan J, Zhang YL, Li B, Cai D. Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis. Nature Communications. 2015 Apr 7;6:67042015.
(Selected for news release by Nature Communications)
Kim M, Yan J, Wu W, Zhang G, Zhang Y, Cai D. Rapid linkage of innate immunological signal to adaptive immunity by the brain-fat axis. Nature Immunology. 16(5): 525-33, 2015.
(Highlighted in News & Views in Nature Immunology, 16(5):440-1, 2015, highlighted in Nature Reviews Immunology 15: 2015)
Yan J, Zhang H, Yin Y, Li J, Purkayastha S, Tang Y, Cai D. Obesity- and aging-induced excess of central TGF-b potentiates diabetic development via an RNA stress response. Nature Medicine, 20(9):1001-8, 2014.
(Highlighted in News and Views in Nature Medicine, 20(9):985-7, 2014, recognized by Faculty 1000, commentary in Nature Reviews Neuroscience 5:563, 2014)
Zhang G, Li J, Purkayastha S, Tang Y, Zhang H, Yin Y, Liu G, Cai D.Hypothalamic Programming of Systemic Aging Involving IKKb/NF-kB and GnRH. Nature, (article), 497(7448): 211-6, 2013.
(Highlighted in News and Views in Nature 497(7448):197-8, 2013)
Li J, Tang Y, Cai D. IKKb/NF-kB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes. Nature Cell Biology, 14(10): 999-1012, 2012.
(Highlighted via Nature Cell Biology preview and news)
Zhang G, Bai H, Zhang H, Dean C, Wu Q, Li J, Guariglia S, Cai D. Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of obesity and metabolic diseases. Neuron, 69 (3): 523-535, 2011.