Exemplary References
NCBI PubMed search of "Hirsch RE"
A Chamchoi, S Srihirun, K Paiboonsukwong, T Sriwantana, P Sathavorasmith, K Pattanapanyasat, RE Hirsch, AN Schechter, N Sibmooh. Decreased nitrite reductase activity of deoxyhemoglobin correlates with platelet activation in hemoglobin E/ß-thalassemia subjects. PLoS One. 13(90):e0203955 pp.1-14 (2018) .
S Jana, F Meng, RE Hirsch, JM Friedman and AI Alayash. “Oxidized Mutant Human Hemoglobins S and E Induce Oxidative Stress and Bioenergetic Dysfunction in Human Pulmonary Endothelial Cells.” Frontiers in Physiology 8: 1-14 (2017)
RE Hirsch, N Sibmooh, S Fucharoen, JM Friedman. “HbE/β-thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms & Novel Therapeutics.” Antioxidants & Redox Signaling 2:794-813 (2017)
EE Bouhassira, HH Billett, ME Fabry, RE Hirsch, R Krishnamoorthy. "The scientific legacy of Ronald L. Nagel (1936-2016), a true renaissance man." American Journal of Hematology 91:865-866 (2016)
MB Strader, T Kassa, F Meng, FB Wood, RE Hirsch, JM Friedman, AI Alayash. "Oxidative instability of hemoglobin E (β26 Glu→Lys) is increased in the presence of free α subunits and reversed by α-hemoglobin stabilizing protein (AHSP): Relevance to HbE/β-thalassemia." Redox Biology 8:363-374 (2016)
CJ Roche, MB Cassera, DD Dantsker, RE Hirsch, JM Friedman. “Generating S-nitrosothiols from Hemoglobin: Mechanisms, Conformational Dependence and Physiological Relevance.” Journal of Biological Chemistry 288:22408-22425 (2013)
QY Chen, ME Fabry, AC Rybicki, SM Suzuka, TC Balazs, Z Etzion, K de Jong, EK Akoto, JE Canterino, DK Kaul, FA Kuypers, D Lefer, EE Bouhassira, and Rhoda Elison Hirsch. “A transgenic mouse model expressing exclusively human hemoglobin E: indications of a mild oxidative stress.” Blood Cells, Molecules and Disease 48:91-101 (2012)
CJ Roche, V Malashkevich, TC Balazs, D Dantsker, QY Chen, J Moreira, SC Almo, JM Friedman, and RE Hirsch. “Structural and Functional Studies Indicating Altered Redox Properties of Hemoglobin E: Implications for Production of Bioactive Nitric Oxide”. Journal of Biological Chemistry 286: 23452-23466 (2011).
J Canterino, O Galkin, PG Vekilov, and RE Hirsch, “ Phase Separation and Crystallization of Hemoglobin C in Transgenic Mouse and Human Erythrocytes.” Biophysical Journal 95:4025-4033 (2008).
E Kiprilov, A Awan, R Desprat, M Velho, CA Clement, AG Byskov, CY Andersen, ST Christensen, P Satir, EE Bouhassira, and RE Hirsch. “Human Embryonic Stem Cells in Culture Possess Primary Cilia with Hedgehog Signaling Machinery.” Journal of Cell Biology J 180:897-904 (2008)
JP Harrington, S Kobayashi, SC Dorman, SL Zito, and RE Hirsch. “Acellular Invertebrate Hemoglobins as Model Therapeutic Oxygen Carriers: Unique Redox Potentials.” Artificial Cells, Blood Substitutes and Biotechnology 35:53-67 (2007)
QY Chen, TC Balazs, RL Nagel, RE Hirsch. Human and mouse hemoglobin association with the transgenic mouse erythrocyte membrane. FEBS Letters 580:4485-4490 (2006).
E Olivier, C Qiu, M Velho, RE Hirsch, EE Bouhassira. Large-scale production of embryonic red blood cells from human embryonic stem cells. Experimental Hematology 34:1635-1642 (2006)
QY Chen and RE Hirsch. A Direct and Simultaneous Detection of Zinc Protoporphyrin IX, Free Protoporphyrin IX, and Fluorescent Heme Degradation Product in Red Blood Cell Hemolysates. Free Radical Research 40:285-294 (2006)
QY Chen, I Lalezari, RL Nagel, and RE Hirsch. “Liganded Hemoglobin Structural Perturbations by the Allosteric Effector L35.” Biophysical Journal 88:2057-2067 (2005).
LN Patskovska, YV Patskovsky, SC Almo, and RE Hirsch. “COHbC and COHbS Crystallize in the R2 Quaternary State at Neutral pH in the Presence of PEG 4000.” Acta Crystallographica D61: 566-573 (2005).
QY Chen, EE Bouhassira, A Besse, S M Suzuka, ME Fabry, RL Nagel, and RE Hirsch. “Generation of Transgenic Mice Expressing Human Hemoglobin E.” Blood Cells, Molecules, and Diseases 33:303-307 (2004).
Y Chen, PG Vekilov, RL Nagel, and RE Hirsch. “Liquid-Liquid Phase Separation in Hemoglobins: Distinct Aggregation Mechanisms of the b6 Mutants. Biophysical Journal 86:1702-1712 (2004).
C Fablet, QY Chen, V Baudin-Creuza, MC Marden, RL Nagel, J Pagnier, and RE Hirsch. “b132K Salt Bridge and Sickle Hemoglobin Stability and Conformation.” British Journal of Haematology 122:317-325 (2003)
RE Hirsch, “Hemoglobin Fluorescence.” Methods in Hemoglobin Disorders Molecular Medicine, pp. 133-154, Humana Press, New Jersey (2003)