Full list of publications at: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47490382/?sort=date&direction=descending
Kao YR, Chen J, Kumari R, Tatiparthy M, Ma Y, Aivalioti MM, Zintiridou A, Thiruthuvanathan V, Reisz JA, Stranski S, Sidoli S, Steidl U, D’Alessandro A, Will B. Cytoplasmic labile iron accumulates in aging stem cells perturbing a key rheostat for identity control. bioRxiv 2021.08.03.454947; doi: https://doi.org/10.1101/2021.08.03.454947
Dong S, Wang Q, Kao YR, Diaz A, Tasset I, Kaushik S, Thiruthuvanathan V, Zintiridou A, Nieves E, Dzieciatkowska M, Reisz JA, Gavathiotis E, D'Alessandro A, Will B*, Cuervo AM*. Chaperone-mediated autophagy sustains haematopoietic stem-cell function. Nature. 2021 Jan 13;. doi: 10.1038/s41586-020-03129-z. [Epub ahead of print] PubMed PMID: 33442062. [* co-corresponding authors]
Kao YR, Chen J, Narayanagari SR, Todorova TI, Aivalioti M, Ferreira M, Ramos-Marques P, Pallaud C, Mantzaris I, Shastri A, Bussel JB, Verma A, Steidl U*, Will B*. Thrombopoietin receptor-independent stimulation of hematopoietic stem cells by eltrombopag. Sci Transl Med. 2018 Sep 12;10(458). doi: 10.1126/scitranslmed.aas9563. PubMed PMID: 30209246. [* co-corresponding authors]
Shastri A*, Choudhary GS, Ferreira-Teixeira M, Gordon-Mitchell S, Ramachandra N, Benard L, Bhattacharyya S, Lopez R, Pradhan K, Giricz O, Ravipati G, Wong L, Cole SL, Bhagat T, Feld J, Dhar J, Bartenstein M, Thiruthuvanathan VJ, Wickrema A, Ye H, Frank DA, Pellagatti A, Boultwood J, Zhou T, Kim Y, MacLeod AR, Epling-Burnette P, Ye M, McCoon P, Woessner R, Steidl U, Will B*, Verma A*. Antisense inhibition of STAT3 as a therapeutic strategy against MDS and AML stem cells. J Clin Invest. 2018 Dec 3;128(12):5479-5488. doi: 10.1172/JCI120156. Epub 2018 Nov 5. PMID: 30252677 [* co-corresponding authors]
Will B*, Vogler TO, Narayanagari S, Bartholdy B, Todorova TI, da Silva Ferreira M, Chen J, Yu Y, Mayer J, Barreyro L, Carvajal L, Neriah DB, Roth M, van Oers J, Schaetzlein S, McMahon C, Edelmann W, Verma A, Steidl U*. Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia. Nat Med. 2015 Oct;21(10):1172-81. PubMed PMID: 26343801. [* co-corresponding authors]
Will B, Vogler TO, Bartholdy B, Garrett-Bakelman F, Mayer J, Barreyro L, Pandolfi A, Todorova TI, Okoye-Okafor UC, Stanley RF, Bhagat TD, Verma A, Figueroa ME, Melnick A, Roth M, Steidl U. Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat Immunol. 2013 May;14(5):437-45. PubMed PMID: 23563689; PubMed Central PMCID: PMC3633104.
Will B, Zhou L, Vogler TO, Ben-Neriah S, Schinke C, Tamari R, Yu Y, Bhagat TD, Bhattacharyya S, Barreyro L, Heuck C, Mo Y, Parekh S, McMahon C, Pellagatti A, Boultwood J, Montagna C, Silverman L, Maciejewski J, Greally JM, Ye BH, List AF, Steidl C, Steidl U, Verma A. Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. Blood. 2012 Sep 6;120(10):2076-86. PubMed PMID: 22753872; PubMed Central PMCID: PMC3437595.
Will B, Siddiqi T, Jordà MA, Shimamura T, Luptakova K, Staber PB, Costa DB, Steidl U, Tenen DG, Kobayashi S. Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells. Blood. 2010 Apr 8;115(14):2901-9. PubMed PMID: 20160166; PubMed Central PMCID: PMC2854433.
Will B, Kawahara M, Luciano JP, Bruns I, Parekh S, Erickson-Miller CL, Aivado MA, Verma A, Steidl U. Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. Blood. 2009 Oct 29;114(18):3899-908. PubMed PMID: 19710504; PubMed Central PMCID: PMC2773490.