Faculty Cancer and Cancer Therapy Steven C. Almo, Ph.D. Professor, Department of Biochemistry Chair Department of Biochemistry Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology Director, Einstein Macromolecular Therapeutics Developmental Facility 718.430.2746steve.almo@einsteinmed.edu View Profile Melissa J. Fazzari, Ph.D., M.S. Associate Professor, Department of Epidemiology & Population Health (Biostatistics) 718.430.8624melissa.fazzari@einsteinmed.edu View Profile Ganjam V. Kalpana, Ph.D. Professor, Department of Genetics Professor, Department of Microbiology & Immunology Mark Trauner Faculty Scholar in Neuro-oncology 718.430.2354ganjam.kalpana@einsteinmed.edu Areas of Research: To understand the role of INI1/hSNF5/SMARCB1, a component of the SWI/SNF complex and a tumor suppressor, in HIV-1 replication and human Cancers using cell culture and mouse models, and to develop novel therapeutic strategies. View Profile Sridhar Mani, M.D. Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Molecular Pharmacology Professor, Department of Genetics 718.430.2871sridhar.mani@einsteinmed.edu Areas of Research: Role of Microbiome-Host Interactions in Physiology and Disease, Orphan Nuclear Receptors in Physiology and Disease, Gastrointestinal Cancer, Drug Discovery and Development View Profile Allison M. Martin, M.D. Assistant Professor, Department of Pediatrics (Pediatric Hematology-Oncology) Assistant Professor, Department of Microbiology & Immunology 718.839.7464allison.martin@einsteinmed.edu View Profile Hayley M. McDaid, Ph.D. Associate Professor, Department of Oncology (Medical Oncology) Associate Professor, Department of Medicine (Oncology & Hematology) Associate Professor, Department of Molecular Pharmacology 718.430.8829hayley.mcdaid@einsteinmed.edu Areas of Research: Breast, Lung and Ovarian Cancer, Experimental Therapeutics, Intrinsic and Acquired Drug Resistance, Tubulin ligands, Cancer and Senescence, Senolytics, Biomarker Development View Profile Jeffrey E. Segall, Ph.D. Professor, Department of Pathology Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research 718.430.2484jeffrey.segall@einsteinmed.edu Areas of Research: mechanisms of tumor cell invasion, intravasation and metastasis; macrophage tumor cell interactions; breast cancer; head and neck cancer; glioblastoma; intravital imaging; KIF9; APOE; cholesterol; neuregulin; JAG1; miR-375 View Profile Simone Sidoli, Ph.D. Assistant Professor, Department of Biochemistry 718.430.3475simone.sidoli@einsteinmed.edu Areas of Research: Chromatin biology, proteomics, mass spectrometry View Profile Xingxing Zang, Ph.D. Professor, Department of Microbiology & Immunology Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Urology Louis Goldstein Swan Chair in Women's Cancer Research 718.430.4155xingxing.zang@einsteinmed.edu Areas of Research: New T cell immune checkpoints; Cancer immunotherapy; Autoimmune diseases and immunotherapy; Metabolic diseases and immunotherapy; Infection and vaccines View Profile Central Nervous System Degeneration and Damage Steven C. Almo, Ph.D. Professor, Department of Biochemistry Chair Department of Biochemistry Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology Director, Einstein Macromolecular Therapeutics Developmental Facility 718.430.2746steve.almo@einsteinmed.edu View Profile Michael Aschner, Ph.D. Professor, Department of Molecular Pharmacology Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Pediatrics Harold & Muriel Block Chair in Molecular Pharmacology Director, Einstein Center of Toxicology 718.430.2317michael.aschner@einsteinmed.edu Areas of Research: Mechanisms of mercury- and manganese-induced neurotoxicity, genetic factors associated with mercury and manganese toxicity, the role of dopamine signaling in susceptibility of dopaminergic neurodegeneration, metals in restless legs syndrome, neurotoxicolo View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Aristea S. Galanopoulou, M.D., Ph.D. Professor, The Saul R. Korey Department of Neurology (Pediatric Neurology) Professor, Dominick P. Purpura Department of Neuroscience 718.430.3791aristea.galanopoulou@einsteinmed.edu Areas of Research: Development of antiepileptogenic and disease modifying therapies for post-traumatic epilepsies; Mechanisms and treatments for epileptic encephalopathies; age and sex specific epileptogenesis; models of lissencephaly View Profile Jean M. Hebert, Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Genetics 718.430.3494jean.hebert@einsteinmed.edu Areas of Research: Devising methods of cell and tissue replacement for the adult neocortex to repair damage or age-related degeneration. View Profile Michael L. Lipton, M.D., Ph.D. Professor, Department of Radiology (Neuroradiology) Professor, Department of Psychiatry and Behavioral Sciences Associate Professor, Dominick P. Purpura Department of Neuroscience Associate Director, Gruss Magnetic Resonance Research Center (MRRC) 718.430.3390michael.lipton@einsteinmed.edu Areas of Research: Neuroimaging, MRI, Brain, Traumatic Brain Injury, Concussion, Image Processing and Analysis, Diffusion Imaging of White Matter Microstructure, Cognitive Dysfunction, Clinical Investigation, MRI Safety, COVID-19 View Profile Mark F. Mehler, M.D. Professor, The Saul R. Korey Department of Neurology Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Psychiatry and Behavioral Sciences Chair The Saul R. Korey Department of Neurology Alpern Family Foundation Chair in Cerebral Palsy Research Director, Institute for Brain Disorders and Neural Regeneration 718.430.3543mark.mehler@einsteinmed.edu Areas of Research: Stem Cell Biology and Regenerative Medicine Epigenetics and Evolutionary Biology Developmental Pathogenesis of Neurodegenerative Diseases Cytokine Biology/Signal Transduction Pathways Neurodevelopmental Disorders (Autism/ASD) View Profile Gaetano Santulli, M.D., Ph.D. Associate Professor, Department of Medicine (Cardiology) Associate Professor, Department of Molecular Pharmacology 718.430.3370gaetano.santulli@einsteinmed.edu Areas of Research: Aging, Cardiology, Endocrinology, Diabetes Mellitus, Gerontology, Heart Failure, Hypertension, Calcium, microRNA, Endothelium, Mitochondria, Exosomes, Angiogenesis, Physiology, Myocardial Infarction, Pancreatic Beta Cells, Fibrosis. View Profile Bridget Shafit-Zagardo, Ph.D. Professor, Department of Pathology 718.430.2189bridget.shafit-zagardo@einsteinmed.edu Areas of Research: Cell signaling mechanisms to halt axonal damage and demyelination via the Gas6, Axl, Tyro3, Mertk, AKT pathways using mouse models of multiple sclerosis. Development of restorative therapies for axons and to enhance remyelination in the CNS. View Profile David J. Sharp, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Ophthalmology & Visual Sciences Professor, Dominick P. Purpura Department of Neuroscience 718.430.3463david.sharp@einsteinmed.edu Areas of Research: We study the roles of microtubules in cell division, motility and morphogenesis. We are developing therapeutics that target microtubule regulators to enhance wound healing, neural regeneration and cardiovascular disease. View Profile Ian M. Willis, Ph.D. Professor, Department of Biochemistry Professor, Department of Systems & Computational Biology 718.430.2839ian.willis@einsteinmed.edu Areas of Research: RNA polymerase III transcription and its repression by Maf1; Mechanisms of obesity resistance in Maf1 knockout mice; Mechanisms of neurodegeneration in Pol III-related leukodystrophy View Profile Zhengdong Zhang, Ph.D. Professor, Department of Genetics 718.678.1139zhengdong.zhang@einsteinmed.edu Areas of Research: Genetics of complex human diseases, Systems biology, Aging, Alzheimer's disease View Profile Eating and Metabolic Disorders Jonathan E. Alpert, M.D., Ph.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Pediatrics Dorothy and Marty Silverman Chair in Psychiatry Chair Department of Psychiatry and Behavioral Sciences 718.430.3080jalpert@montefiore.org View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Kelvin Davies, Ph.D. Professor, Department of Urology Professor, Department of Molecular Pharmacology 718.430.3201kelvin.davies@einsteinmed.edu View Profile Rachel A. Ross, M.D., Ph.D. Assistant Professor, Dominick P. Purpura Department of Neuroscience Assistant Professor, Department of Psychiatry and Behavioral Sciences Assistant Professor, Department of Medicine 718.430.3134rachel.ross@einsteinmed.edu Areas of Research: Stress, autonomic nervous system, neuroendocrinology, neuropeptides, systems neuroscience, metabolism, nutrient state, sex differences, obesity, eating disorders View Profile Simone Sidoli, Ph.D. Assistant Professor, Department of Biochemistry 718.430.3475simone.sidoli@einsteinmed.edu Areas of Research: Chromatin biology, proteomics, mass spectrometry View Profile Sylvia O. Suadicani, Ph.D. Associate Professor, Department of Urology Associate Professor, Department of Molecular Pharmacology Assistant Professor, Dominick P. Purpura Department of Neuroscience 718.430.3225sylvia.suadicani@einsteinmed.edu Areas of Research: Urogenital Dysfunction in Diabetes, Multiple Sclerosis, Spinal Cord Injury, Estrogen Deficiency, Aging, Overactive & Underactive Bladder, Female Sexual Dysfunction; Chronic Pelvic Pain; Interstitial Cystitis; Bladder Cancer View Profile Ji Ying Sze, Ph.D. Associate Professor, Department of Molecular Pharmacology 718.430.2084jiying.sze@einsteinmed.edu Areas of Research: Regulatory mechanisms of early postnatal cortical gene expression in neural circuit development and psychiatric disorders, with a focus on the role of serotonin uptake transporter and early life drug exposure. View Profile Ian M. Willis, Ph.D. Professor, Department of Biochemistry Professor, Department of Systems & Computational Biology 718.430.2839ian.willis@einsteinmed.edu Areas of Research: RNA polymerase III transcription and its repression by Maf1; Mechanisms of obesity resistance in Maf1 knockout mice; Mechanisms of neurodegeneration in Pol III-related leukodystrophy View Profile Yunlei Yang, M.D., Ph.D. Associate Professor, Department of Medicine (Endocrinology) Associate Professor, Dominick P. Purpura Department of Neuroscience 718.430.8570yunlei.yang@einsteinmed.edu Areas of Research: Glial and neuronal mechanisms of adipose tissue lipid metabolism and affective behaviors. Neural circuits orchestrating brain-adipose tissue communications. Key words: Astrocyte; Neural circuits; Adipose tissue; Anxiety; Depression; Diabetes; Obesity View Profile Infectious Diseases and Autoimmunity Jonathan E. Alpert, M.D., Ph.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Pediatrics Dorothy and Marty Silverman Chair in Psychiatry Chair Department of Psychiatry and Behavioral Sciences 718.430.3080jalpert@montefiore.org View Profile Julia H. Arnsten, M.D., M.P.H. Professor, Department of Medicine (General Internal Medicine) Professor, Department of Epidemiology & Population Health Professor, Department of Psychiatry and Behavioral Sciences Chief, Division of General Internal Medicine Director, Center for Comparative Effectiveness Research 718.920.6641jarnsten@montefiore.org View Profile Joan W. Berman, Ph.D. Professor, Department of Pathology Professor, Department of Microbiology & Immunology Irving D. Karpas Chair in Medicine Senior Academic Advisor to the Sue Golding Graduate Division 718.430.2587joan.berman@einsteinmed.edu Areas of Research: We study CNS HIV infection and neuroAIDS. We examine cells & fluids from HIV+ people for HIV RNA, DNA, functions, and predictors of cognitive deficits. We correlate these with imaging, cognitive testing, and clinical data. View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Johanna P. Daily, M.D., M.S. Professor, Department of Medicine (Infectious Diseases) Professor, Department of Microbiology & Immunology 718.678.1176johanna.daily@einsteinmed.edu Areas of Research: We study the biology and host response to Plasmodium falciparum infection. We study naturally infected cohorts using comprehensive genetic and metabolic approaches to guide laboratory based pathogenesis and immunology studies View Profile Ganjam V. Kalpana, Ph.D. Professor, Department of Genetics Professor, Department of Microbiology & Immunology Mark Trauner Faculty Scholar in Neuro-oncology 718.430.2354ganjam.kalpana@einsteinmed.edu Areas of Research: To understand the role of INI1/hSNF5/SMARCB1, a component of the SWI/SNF complex and a tumor suppressor, in HIV-1 replication and human Cancers using cell culture and mouse models, and to develop novel therapeutic strategies. View Profile Vinayaka R. Prasad, Ph.D. Professor, Department of Microbiology & Immunology 718.430.2517vinayaka.prasad@einsteinmed.edu Areas of Research: Role of extrinsic factors such as CCL2 in the modulation of ESCRT factors to enhance HIV-1 budding and release; Effect of drugs of abuse on HIV replication and HAND; Viral determinants of HIV associated neurocognitive disorders (HAND) View Profile Anjali Sharma, M.D., M.S. Professor, Department of Medicine (General Internal Medicine) 718.882.2714anjali.sharma@einsteinmed.edu Areas of Research: metabolic complications of HIV, HIV infection in women, HIV and aging, HIV and substance abuse View Profile Simone Sidoli, Ph.D. Assistant Professor, Department of Biochemistry 718.430.3475simone.sidoli@einsteinmed.edu Areas of Research: Chromatin biology, proteomics, mass spectrometry View Profile David C. Spray, Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Medicine (Cardiology) 718.430.2537david.spray@einsteinmed.edu View Profile Joanna L. Starrels, M.D., M.S. Professor, Department of Medicine (General Internal Medicine) Professor, Department of Psychiatry and Behavioral Sciences 718.920.7174jostarre@montefiore.org Areas of Research: Opioid management for patients with chronic pain, opioid tapering, treatment agreements, urine drug testing, medical cannabis, collaborative care models, opioid use disorder, opioid use in HIV care. View Profile Innovative Technologies Steven C. Almo, Ph.D. Professor, Department of Biochemistry Chair Department of Biochemistry Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology Director, Einstein Macromolecular Therapeutics Developmental Facility 718.430.2746steve.almo@einsteinmed.edu View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Melissa J. Fazzari, Ph.D., M.S. Associate Professor, Department of Epidemiology & Population Health (Biostatistics) 718.430.8624melissa.fazzari@einsteinmed.edu View Profile Herbert M. Lachman, M.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Department of Medicine (Oncology & Hematology) Associate Professor, Dominick P. Purpura Department of Neuroscience Associate Professor, Department of Genetics 718.430.2428herb.lachman@einsteinmed.edu Areas of Research: We use induced pluripotent stem cell technology to study the molecular basis of schizophrenia and autism by RNA-seq and ChIP-seq. Patient-specific lines and isogenic knockout lines, generated by CRISP-Cas9 are used. View Profile Michael L. Lipton, M.D., Ph.D. Professor, Department of Radiology (Neuroradiology) Professor, Department of Psychiatry and Behavioral Sciences Associate Professor, Dominick P. Purpura Department of Neuroscience Associate Director, Gruss Magnetic Resonance Research Center (MRRC) 718.430.3390michael.lipton@einsteinmed.edu Areas of Research: Neuroimaging, MRI, Brain, Traumatic Brain Injury, Concussion, Image Processing and Analysis, Diffusion Imaging of White Matter Microstructure, Cognitive Dysfunction, Clinical Investigation, MRI Safety, COVID-19 View Profile Simone Sidoli, Ph.D. Assistant Professor, Department of Biochemistry 718.430.3475simone.sidoli@einsteinmed.edu Areas of Research: Chromatin biology, proteomics, mass spectrometry View Profile Zhengdong Zhang, Ph.D. Professor, Department of Genetics 718.678.1139zhengdong.zhang@einsteinmed.edu Areas of Research: Genetics of complex human diseases, Systems biology, Aging, Alzheimer's disease View Profile Psychiatric Disorders Jonathan E. Alpert, M.D., Ph.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Pediatrics Dorothy and Marty Silverman Chair in Psychiatry Chair Department of Psychiatry and Behavioral Sciences 718.430.3080jalpert@montefiore.org View Profile Julia H. Arnsten, M.D., M.P.H. Professor, Department of Medicine (General Internal Medicine) Professor, Department of Epidemiology & Population Health Professor, Department of Psychiatry and Behavioral Sciences Chief, Division of General Internal Medicine Director, Center for Comparative Effectiveness Research 718.920.6641jarnsten@montefiore.org View Profile Vilma Gabbay, M.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Dominick P. Purpura Department of Neuroscience Director, Psychiatry Research Institute at Montefiore Einstein (PRIME) 718.839.7549vilma.gabbay@einsteinmed.edu Areas of Research: Dr. Gabbay's primary areas of research include multimodal studies of adolescent depression and reward deficits, the comorbidity of depression and substance use people living with HIV, and neuropsychiatric sequelae of COVID-19. View Profile J. Tiago Goncalves, Ph.D. Assistant Professor, Dominick P. Purpura Department of Neuroscience 718.430.8524tiago.goncalves@einsteinmed.edu Areas of Research: Adult neurogenesis; Neuronal development; Learning and Memory; Aging View Profile Herbert M. Lachman, M.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Department of Medicine (Oncology & Hematology) Associate Professor, Dominick P. Purpura Department of Neuroscience Associate Professor, Department of Genetics 718.430.2428herb.lachman@einsteinmed.edu Areas of Research: We use induced pluripotent stem cell technology to study the molecular basis of schizophrenia and autism by RNA-seq and ChIP-seq. Patient-specific lines and isogenic knockout lines, generated by CRISP-Cas9 are used. View Profile Chaim Putterman, M.D. Professor, Department of Medicine (Rheumatology) Professor, Department of Microbiology & Immunology 718.430.4266chaim.putterman@einsteinmed.edu Areas of Research: Mechanisms of autoimmunity; Pathogenesis of kidney and neuropsychiatric disease in systemic lupus erythematous (SLE), including anti-DNA antibodies, macrophages, and cytokines; Novel therapies for lupus; SLE biomarkers View Profile Jelena Radulovic, M.D., Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Psychiatry and Behavioral Sciences Director, Psychiatry Research Institute at Montefiore Einstein (PRIME) Sylvia and Robert S. Olnick Chair in Neuroscience 718.430.8510jelena.radulovic@einsteinmed.edu View Profile Rachel A. Ross, M.D., Ph.D. Assistant Professor, Dominick P. Purpura Department of Neuroscience Assistant Professor, Department of Psychiatry and Behavioral Sciences Assistant Professor, Department of Medicine 718.430.3134rachel.ross@einsteinmed.edu Areas of Research: Stress, autonomic nervous system, neuroendocrinology, neuropeptides, systems neuroscience, metabolism, nutrient state, sex differences, obesity, eating disorders View Profile Ji Ying Sze, Ph.D. Associate Professor, Department of Molecular Pharmacology 718.430.2084jiying.sze@einsteinmed.edu Areas of Research: Regulatory mechanisms of early postnatal cortical gene expression in neural circuit development and psychiatric disorders, with a focus on the role of serotonin uptake transporter and early life drug exposure. View Profile Yunlei Yang, M.D., Ph.D. Associate Professor, Department of Medicine (Endocrinology) Associate Professor, Dominick P. Purpura Department of Neuroscience 718.430.8570yunlei.yang@einsteinmed.edu Areas of Research: Glial and neuronal mechanisms of adipose tissue lipid metabolism and affective behaviors. Neural circuits orchestrating brain-adipose tissue communications. Key words: Astrocyte; Neural circuits; Adipose tissue; Anxiety; Depression; Diabetes; Obesity View Profile Sensory and Autonomic Disorders Steven C. Almo, Ph.D. Professor, Department of Biochemistry Chair Department of Biochemistry Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology Director, Einstein Macromolecular Therapeutics Developmental Facility 718.430.2746steve.almo@einsteinmed.edu View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Kelvin Davies, Ph.D. Professor, Department of Urology Professor, Department of Molecular Pharmacology 718.430.3201kelvin.davies@einsteinmed.edu View Profile Vilma Gabbay, M.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Dominick P. Purpura Department of Neuroscience Director, Psychiatry Research Institute at Montefiore Einstein (PRIME) 718.839.7549vilma.gabbay@einsteinmed.edu Areas of Research: Dr. Gabbay's primary areas of research include multimodal studies of adolescent depression and reward deficits, the comorbidity of depression and substance use people living with HIV, and neuropsychiatric sequelae of COVID-19. View Profile Sridhar Mani, M.D. Professor, Department of Oncology (Medical Oncology) Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Molecular Pharmacology Professor, Department of Genetics 718.430.2871sridhar.mani@einsteinmed.edu Areas of Research: Role of Microbiome-Host Interactions in Physiology and Disease, Orphan Nuclear Receptors in Physiology and Disease, Gastrointestinal Cancer, Drug Discovery and Development View Profile Jelena Radulovic, M.D., Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Psychiatry and Behavioral Sciences Director, Psychiatry Research Institute at Montefiore Einstein (PRIME) Sylvia and Robert S. Olnick Chair in Neuroscience 718.430.8510jelena.radulovic@einsteinmed.edu View Profile Gaetano Santulli, M.D., Ph.D. Associate Professor, Department of Medicine (Cardiology) Associate Professor, Department of Molecular Pharmacology 718.430.3370gaetano.santulli@einsteinmed.edu Areas of Research: Aging, Cardiology, Endocrinology, Diabetes Mellitus, Gerontology, Heart Failure, Hypertension, Calcium, microRNA, Endothelium, Mitochondria, Exosomes, Angiogenesis, Physiology, Myocardial Infarction, Pancreatic Beta Cells, Fibrosis. View Profile Julie Secombe, Ph.D. Professor, Department of Genetics Professor, Dominick P. Purpura Department of Neuroscience 718.430.2698julie.secombe@einsteinmed.edu Areas of Research: Chromatin and gene expression; KDM5 histone demethylase-regulated transcription; KDM5-mediated intellectual disability; Myc oncogene-induced growth and genome instability; Linking Myc to activation of transposons and aging. View Profile David J. Sharp, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Ophthalmology & Visual Sciences Professor, Dominick P. Purpura Department of Neuroscience 718.430.3463david.sharp@einsteinmed.edu Areas of Research: We study the roles of microtubules in cell division, motility and morphogenesis. We are developing therapeutics that target microtubule regulators to enhance wound healing, neural regeneration and cardiovascular disease. View Profile Deepika E. Slawek, M.D., M.S. Assistant Professor, Department of Medicine (General Internal Medicine) 718.920.3786dslawek@montefiore.org Areas of Research: I study how medical cannabis affects chronic pain and inflammation in people living with HIV. View Profile David C. Spray, Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Medicine (Cardiology) 718.430.2537david.spray@einsteinmed.edu View Profile Sylvia O. Suadicani, Ph.D. Associate Professor, Department of Urology Associate Professor, Department of Molecular Pharmacology Assistant Professor, Dominick P. Purpura Department of Neuroscience 718.430.3225sylvia.suadicani@einsteinmed.edu Areas of Research: Urogenital Dysfunction in Diabetes, Multiple Sclerosis, Spinal Cord Injury, Estrogen Deficiency, Aging, Overactive & Underactive Bladder, Female Sexual Dysfunction; Chronic Pelvic Pain; Interstitial Cystitis; Bladder Cancer View Profile Tissue Stem Cells and Central Nervous System Repair Eric E. Bouhassira, Ph.D. Professor, Department of Cell Biology Professor, Department of Medicine (Oncology & Hematology) Professor, Department of Oncology (Hematology) Ingeborg and Ira Leon Rennert Professor of Stem Cell Biology and Regenerative Medicine 718.430.2188eric.bouhassira@einsteinmed.edu Areas of Research: Pluripotent stem cells, erythroid differentiation, red blood cells, gene therapy, hemoglobinopathies, genome modification, TTP, hemophilia A View Profile Dongsheng Cai, M.D., Ph.D. Professor, Department of Molecular Pharmacology Young Men's Division Chair in Physiology Director, Institute for Neuroimmunology and Inflammation 718.430.2426dongsheng.cai@einsteinmed.edu Areas of Research: Neuroimmunology, neuroendocrinology and neural stem cell biology in physiology and disease. View Profile Kelvin Davies, Ph.D. Professor, Department of Urology Professor, Department of Molecular Pharmacology 718.430.3201kelvin.davies@einsteinmed.edu View Profile J. Tiago Goncalves, Ph.D. Assistant Professor, Dominick P. Purpura Department of Neuroscience 718.430.8524tiago.goncalves@einsteinmed.edu Areas of Research: Adult neurogenesis; Neuronal development; Learning and Memory; Aging View Profile Jean M. Hebert, Ph.D. Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Genetics 718.430.3494jean.hebert@einsteinmed.edu Areas of Research: Devising methods of cell and tissue replacement for the adult neocortex to repair damage or age-related degeneration. View Profile Herbert M. Lachman, M.D. Professor, Department of Psychiatry and Behavioral Sciences Professor, Department of Medicine (Oncology & Hematology) Associate Professor, Dominick P. Purpura Department of Neuroscience Associate Professor, Department of Genetics 718.430.2428herb.lachman@einsteinmed.edu Areas of Research: We use induced pluripotent stem cell technology to study the molecular basis of schizophrenia and autism by RNA-seq and ChIP-seq. Patient-specific lines and isogenic knockout lines, generated by CRISP-Cas9 are used. View Profile Mark F. Mehler, M.D. Professor, The Saul R. Korey Department of Neurology Professor, Dominick P. Purpura Department of Neuroscience Professor, Department of Psychiatry and Behavioral Sciences Chair The Saul R. Korey Department of Neurology Alpern Family Foundation Chair in Cerebral Palsy Research Director, Institute for Brain Disorders and Neural Regeneration 718.430.3543mark.mehler@einsteinmed.edu Areas of Research: Stem Cell Biology and Regenerative Medicine Epigenetics and Evolutionary Biology Developmental Pathogenesis of Neurodegenerative Diseases Cytokine Biology/Signal Transduction Pathways Neurodevelopmental Disorders (Autism/ASD) View Profile Bridget Shafit-Zagardo, Ph.D. Professor, Department of Pathology 718.430.2189bridget.shafit-zagardo@einsteinmed.edu Areas of Research: Cell signaling mechanisms to halt axonal damage and demyelination via the Gas6, Axl, Tyro3, Mertk, AKT pathways using mouse models of multiple sclerosis. Development of restorative therapies for axons and to enhance remyelination in the CNS. View Profile David J. Sharp, Ph.D. Professor, Department of Molecular Pharmacology Professor, Department of Ophthalmology & Visual Sciences Professor, Dominick P. Purpura Department of Neuroscience 718.430.3463david.sharp@einsteinmed.edu Areas of Research: We study the roles of microtubules in cell division, motility and morphogenesis. We are developing therapeutics that target microtubule regulators to enhance wound healing, neural regeneration and cardiovascular disease. View Profile Simone Sidoli, Ph.D. Assistant Professor, Department of Biochemistry 718.430.3475simone.sidoli@einsteinmed.edu Areas of Research: Chromatin biology, proteomics, mass spectrometry View Profile