Animal Biohazard The Animal Biohazard Core provides a state-of-the-art, safe and efficient biosafety level 3 (BSL3) laboratory for conducting experiments involving in vivo modeling of infectious diseases. The core staff has extensive experience in animal studies that use BSL2/3 pathogens including Mycobacterium tuberculosis. HIV transgenic mice are also used. The core will guide and support investigators in the use of in vivo models of infectious diseases caused by virulent pathogens. Services Access the Services INFECTION BY AERGENIC CHALLENGE:Delivery of microbes directly into the lungs using the "Wisconsin" chamber or the “nose-only” In-Tox aerosolization apparatus PROVISION OF SPECIALTY ANIMAL STRAINS ANIMAL PROCEDURES:Post-mortem dissection for the procurement of organs, tissue preparation, blood drawing, delivery in vivo of pharmacological or biological agents EXPERIMENTAL DESIGN AND TRAINING:Assist in experimental design for studies involving in vivo animal modeling, and train and help researchers in carrying out animal procedures BIOHAZARD BARRIER HOUSING:Provide husbandry for mice infected with HIV and various AIDS-related pathogens Related Shared Facilities Biohazard Immunology/Pathology CoreClinical and Molecular Virology CoreHistotechnology and Comparative Pathology Facility Center Affiliations Einstein-Montefiore Center for AIDS Research (CFAR) Selected Publications Infection and Immunity, 2008 Sep;76(9):4269-81 Journal of Virology, 2008;82:3078-89 Journal of Virology, 2008;82:5562-72 Plos Pathogens, 2008: 4(6):e1000081 Location and Contacts Animal Biohazard Chanin 622; Price/Block 570 John Chan, M.D.Director718-430-2746john.chan@einsteinmed.orgLawrence Herbst, D.V.M., Ph.D.Co-Director718-430-8553lawrence.herbst@einsteinmed.org