Uses
BTTP is designed for proteomics applications and for labeling intracellular proteins in bacteria. BTTPS and BTTAA are for live cell surface labeling.The ligands are available from our core facility for a small fee.
Purchasing Ligands
The Chemical Synthesis Core uses iLab to accept orders and to bill. To order ligands from the facility, please either log-in with your existing iLab account or sign up for an account on our iLab page.
Further reading
Biocompatible copper(I) catalysts for in vivo imaging of glycans. Soriano del Amo, D.; Wang, W.; Jiang, H.; Besanseney, C.; Yan, A, C.; Levy, M.; Liu, Y.; Marlow, F. Wu, P. J. Am. Chem. Soc. 2010, 132, 16893.
Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study. Besanceney, C.; Jiang, H.; Zheng, T.; Feng, Lei; Soriano Del Amo, D.; Klivansky, L.; Liu, Y.; Marlow, F.; Wu, P. Angew. Chem. Int. Ed. 2011, 50, 8051.
Sulfated ligands for the Copper(I)-catalyzed Azide-Alkyne Cycloaddition. Wang, W.; Hong, S.; Tran, A.; Jiang, H.; Triano, R.; Liu, Y. Chen, X.; Wu, P. Chem. Asian J. The “Click Chemistry 10 Years” Special Issue. 2011, 10, 2796.
Biocompatible Click Chemistry Enabled Labeling of Cytosolic Proteins and Compartment-specific pH Indicators. Yang, M.; Jalloh, A.; Wei, W. Zhao, J.*; Wu. P*; Chen, P.R.* Nature Comm. 2014, 5, Article number: 4981; doi:10.1038/ncomms5981 (*co- corresponding authors).
Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Jiang, H.; Zheng, T.; Lopez-Aguilar, A.; Feng, L.; Kopp, F.; Marlow, F. and Wu, P. Bioconjugate Chem. 2014, 25, 698−706.