Experimental Drug Boosts Brain Cell Cleaning to Reverse Alzheimer's Disease Symptoms in Mice
Genetic Engineering & Biotechnology News - April 23, 2021
Ana Maria Cuervo, M.D., Ph.D., discusses her novel drug that revs up a cellular cleaning process and was found to reverse key symptoms of Alzheimer's disease in mice. Dr. Cuervo is professor of developmental and molecular biology, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
Additional Coverage includes New Atlas, Fierce Biotech, ANSA, El Nacional, and CBS affiliates
Boosting Blood Stem Cell Housekeeping Reversed Immunity Decline in Aging Mice
National Institute on Aging - March 11, 2021
Research led by Ana Maria Cuervo, M.D., Ph.D., has found that improving autophagy, the process by which cells recycle and remove waste, in blood stem cells can reverse age-related declines in the immune systems of mice—findings that may have relevance for human health. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
New York Times interviews Ana Maria Cuervo, M.D., Ph.D., about the scientist awarded the Nobel Prize for his discoveries on how cells recycle, known as autophagy. Dr. Cuervo is a leader in this field of research, focusing on chaperone-mediated autophagy. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
More coverage on this story
The Wall Street Journal
October 5, 2016
U.S. News & World Report interviews Ana Maria Cuervo, M.D., Ph.D., and Nir Barzilai, M.D., about their aging research. Drs. Cuervo and Barzilai are co-directors of Einstein’s Institute for Aging Research.
August 9, 2016
Scientific American interviews Ana Maria Cuervo, M.D., Ph.D., about her research connecting defective proteins, neurodegenerative diseases and a cellular cleaning process.
August 1, 2016
Nature interviews Ana Maria Cuervo, M.D., Ph.D., about her research on autophagy, a critical cellular recycling process linked to numerous diseases. Dr. Cuervo’s numerous contributions in the field are detailed, including implicating faulty autophagy in Parkinson’s disease and discovering its role in regulating hunger in the brain and metabolism in the liver. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
October 16, 2014
The Scientist profiles Ana Maria Cuervo, M.D., Ph.D., detailing her career path and research in autophagy. The career retrospective follows Dr. Cuervo’s career from her first medical student project in Spain to her arrival at Einstein. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
November 1, 2013
New Parkinson's research led by Ana Maria Cuervo, M.D., Ph.D., was highlighted by Francis Collins, M.D., Ph.D., in his NIH Director's Blog. Dr. Cuervo’s recent study, published in Nature Neuroscience, found that a clog in the cell's protein disposal system may be a cause of the disease. Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine and the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
March 12, 2013
Science magazine interviews Ana Maria Cuervo, M.D., Ph.D., about recent research on autophaghy, the cell’s natural recycling process that keeps cells cleans and uncluttered. Dr. Cuervo is professor of developmental and molecular biology and of anatomy and structural biology.
December 9, 2011
Seattle NPR station KUOW interviews Nir Barzilai, M.D., and Ana Maria Cuervo, M.D., Ph.D., about the biology of aging and the genetics of longevity. Dr. Cuervo discussed autophagy, the process of cell regulation, and the role it plays in keeping organs young, potentially leading to longer life spans. Dr. Barzilai discussed his genetic research with centenarians and the importance of discovering the key to healthy aging. Dr. Cuervo is professor of developmental and molecular biology. Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of the Institute for Aging Research.
April 8, 2011
The New York Times interviews Ana Maria Cuervo, M.D., Ph.D., on the self-destructive behaviors of cells and how they may hold the key to longevity. Research suggests that autophagy, the process of cell regulation, could hold the key to preventing disease and lead to longer life spans. Dr. Cuervo is professor of developmental and molecular biology.
October 6, 2009
About.com highlights a $10 million NIH grant Einstein received to study how organs age. A consortium of four researchers led by Ana Maria Cuervo, M.D., Ph.D., will examine the molecular processes that contribute to aging. The other members of the Einstein consortium are Laura Santambrogio, M.D., Ph.D., associate professor of pathology; Fernando Macian-Juan, M.D., Ph.D., assistant professor of pathology; and Mark J. Czaja, M.D., professor of medicine.
March 2, 2009