Researchers Have Found a Way to Improve TB Vaccine
NPR - January 02, 2020
William Jacobs Jr., Ph.D., comments on a study in which high doses of the tuberculosis vaccine injected directly into the bloodstream of monkeys provided nearly complete immunity to the disease. Dr. Jacobs is professor of microbiology & immunology and of genetics and the Leo and Julia Forchheimer Chair in Microbiology & Immunology at Einstein.
Science News interviews Betsy Herold, M.D., about her new research with William Jacobs, Jr., Ph.D., on an experimental herpes vaccine. Dr. Herold explains that their novel approach was to silence the loud, or dominant, surface protein on the virus in order to use the other proteins to trigger an effective immune response. Dr. Herold holds the Harold and Muriel Block Chair in Pediatrics at Einstein and is the chief of the division of pediatric infectious diseases at the Children's Hospital at Montefiore and Einstein. Dr. Jacobs is a Howard Hughes Medical Institute Investigator and the Leo and Julia Forchheimer Chair in Microbiology & Immunology at Einstein.
March 10, 2015
In a Nautilus profile, Dr. William Jacobs, Jr., discusses the key breakthroughs in his tuberculosis research and how losing his vision impacted his career path. The feature also includes an audio interview and animation of Dr. Jacobs talking about his shift from mathematics to bacterial genetics, his desire to help the underprivileged, and his goal to see the eradication of TB in his lifetime. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein and a Howard Hughes Medical Institute investigator.
March 31, 2014
The American Association for the Advancement of Science features William Jacobs, Jr., Ph.D., dubbed the “TB Terminator,” on its “Member Spotlight” blog. The profile highlights Dr. Jacobs’ pioneering use of molecular genetics to control TB, his drive to discover a new vaccine and his work to encourage student interest – from high school to the master’s level – in science. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein and a Howard Hughes Medical Institute investigator.
September 4, 2012
TheScientist features an inexpensive new test developed by William Jacobs, Jr., Ph.D., and a team of researchers that quickly detects tuberculosis and determines whether it is drug resistant, a process that currently takes months and may result in death. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein and a Howard Hughes Medical Institute investigator.
February 14, 2012
BBC News (UK) interviews William Jacobs, Jr., Ph.D., about his new study that identifies a promising new vaccine to protect against tuberculosis. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein and a Howard Hughes Medical Institute investigator.
More coverage on this story
The Independent (UK)
Agence France-Presse
Agenzia Italia (Italy)
UPI
September 6, 2011
The Financial Times (UK) features research by William Jacobs, Jr., Ph.D., that identifies two new ways to fight tuberculosis (TB), a disease responsible for an estimated two million deaths each year. Dr. Jacobs' work uncovered enzymes that, when disabled, lead the bacteria that causes TB to self-destruct. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein and a Howard Hughes Medical Institute investigator. (Log in required)
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Telegraph (UK)
UPI
BBC Mundo (in Spanish)
March 22, 2010