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Augmenting Medical Education—Managing patients with intellectual and developmental disabilities (IDD) is seldom included in medical education, yet these individuals often have more long-term conditions and higher healthcare costs. To address this issue, a team led by Joanne Siegel used funding from the American Academy of Developmental Medicine and Dentistry (AADMD) and Special Olympics International to develop curriculum focused on treating IDD patients. Vincent Siasoco, M.D., also aided Einstein students in establishing a student chapter of the AADMD. The program, now permanently part of second-year curriculum, demonstrates Einstein’s leadership in inclusive medical education aimed at reducing healthcare disparities in patients with IDD. The duo highlighted their work in an article they co-wrote for Exceptional Parent Magazine. Ms. Siegel is principle associate in pediatrics and co-director of the Rose F. Kennedy Center University Center of Excellence in Developmental Disabilities. Dr. Siasoco is assistant professor of family & social medicine and of pediatrics, and director of primary care at the Kennedy Center’s Children’s Evaluation and Rehabilitation Center.

Wednesday, December 15, 2021
 

At the 'Head' of Migraine Research—Migraines are estimated to affect one billion people worldwide, costing over $15 billion in medical expenses in the United States alone. Uncovering the pathophysiology of and novel treatments for migraines are critically important. A recent analysis of 6,327 publications focused on migraine research, published in the Annals of Palliative Medicine, identified Einstein as the most-published institution in the field. It also found Richard Lipton, M.D., to be the most frequently published researcher on the topic in the world. His colleague Dawn Buse, Ph.D., was ranked fourth. Their work contributed to greater understanding of migraine prevalence and treatment efficacy. The scholarly review establishes Einstein’s global leadership in migraine research, led by Drs. Lipton and Buse. Each is a professor in the Saul R. Korey Department of Neurology at Einstein. Dr. Lipton also is vice chair in that department, as well as professor of psychiatry & behavioral science and of epidemiology & population health. He holds the Edwin S. Lowe Chair in Neurology as well, and is director of the Montefiore Headache Center

Wednesday, December 08, 2021
 

Insights on Cardiovascular Disease—Carlos J. Rodriguez M.D., M.P.H. is co-editor (with Keith Ferdinand, M.D., and Herman Taylor, Jr., M.D., M.P.H.), of the latest edition of Cardiovascular Disease in Racial and Ethnic Minority Populations (Springer).  Available as an e-book in PDF format and as a hardcover textbook, the publication is part of the Contemporary Cardiology series edited by Peter Toth, M.D., M.P.H., and is a helpful resource for general practitioners caring for patients with cardiovascular disease, including determining when it would serve the patient best to refer them to a cardiologist. Its content covers the impact of genetics, social determinants of health, the environment, and lifestyle on cardiovascular conditions in African-American and Hispanic/Latinx populations. Dr. Rodriguez is professor of medicine (cardiology), and of epidemiology and population health at Einstein, and director of clinical cardiology research and of cardiovascular epidemiology at Montefiore.

Wednesday, November 24, 2021
 

ExCITING News—Ana Maria Cuervo, M.D., Ph.D.Jeffrey Pollard, Ph.D., and the late Paul Frenette, M.D., have been named to Clariviate Analytic's Highly Cited Researchers 2021 list.The list identifies researchers who demonstrated significant influence in their chosen field or fields through the publication of multiple highly cited papers during the last decade. Their names are drawn from the publications that rank in the top 1% by citations for field and publication year in the Web of Science™ citation index. Dr. Frenette was named in the field of immunology, Dr. Cuervo and Dr. Pollard, who has a second affiliation with Einstein, earned the honor in the "cross-field" category. Dr. Cuervo is co-director of the Einstein Institute for Aging Research, and professor of medicine, of developmental & molecular biology, and of anatomy & structural biology. She also is the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases. Dr. Pollard is professor emeritus of developmental & molecular biology and of obstetrics & gynecology and women's health and the Louis Goldstein Swan Chair in Women's Cancer Research Emeritus. Dr. Frenette is former chair and director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, and was professor of medicine and of cell biology

Friday, November 19, 2021
 

Resourceful Research—Plastic and Reconstructive Surgery (PRS), the official journal of the American Society of Plastic Surgeons, presented Oren Tepper M.D., with its 2021 PRS Best Paper award. The article for which Dr. Tepper was honored had appeared in the PRS’s December 2020 issue. It detailed the virtues of the iPhone X as a viable resource for plastic surgeons to use when doing three-dimensional (3-D) facial scanning. In the paper, Dr. Tepper described the phone’s attributes, including it being a cheaper and readily accessible option, and its ability to provide accurate and precise 3-D data. He concluded that the 3-D technology of the phone is highly valuable to plastic surgeons during virtual surgical planning sessions, and it fits in the palm of their hands. Dr. Tepper is associate professor of surgery (plastic and reconstructive) at Einstein and director of aesthetic surgery at Montefiore.

Monday, November 08, 2021
 

Influential Research Pioneer—The Metastasis Research Society has given John Condeelis, Ph.D., its I.J. "Josh" Fidler Innovation in Metastasis Research Award, for his significant contributions to metastasis research. Since 2012, this biennial award has gone to an investigator whose work has substantially influenced the field. Dr. Condeelis has published more than 350 scientific publications, primarily focused on biophotonics, tumor cell motility and invasion, and metastasis. By combining high-resolution in-vivo microscopy, multi-photon imaging, and gene expression analysis, Dr. Condeelis has uncovered key molecular mechanisms driving tumor cells’ invasive abilities. His latest discoveries reported in Nature Communications, reveal the cells and the signaling pathways that transform breast-cancer tumor cells into invasive cancer stem cells responsible for metastasis—findings that could lead to treatment strategies for preventing metastasis from occurring. Dr. Condeelis is professor and co-chair of anatomy and structural biology, professor of surgery where he is director of the program in Basic and Translational Research, and co-director of the Gruss Lipper Biophotonics Center and Integrated Imaging Program. He also holds the Judith and Burton P. Resnick Chair in Translational Research. 

Thursday, November 04, 2021
 

Recognizing Excellence—Robert Singer, Ph.D., has received the 51st Rosenstiel Award for Distinguished Work in Basic Medical Research. A panel of scientists appointed by the director of the Rosenstiel Basic Medical Sciences Research Center at Brandeis University recognized Dr. Singer for his key role in revealing the dynamics of gene expression using high-resolution imaging. This work has enabled researchers to visualize and characterize gene expression at single-molecule resolution and to follow the subcellular choreography of diverse messenger RNAs “from cradle to grave”—from its transcription to its translation to its degradation. Dr. Singer is professor and co-chair of anatomy and structural biology as well as professor in the Dominick P. Purpura Department of Neuroscience and of cell biology, and co-director of the Gruss-Lipper Biophotonics Center and of the Integrated Imaging Program. He also holds the Harold and Muriel Block Chair in Anatomy and Structural Biology.

Tuesday, November 02, 2021
 

Award to Tackle Lung Cancer—Cancer immunotherapy is a treatment strategy that “takes the brakes off” immune cells so they can attack cancer cells. These therapies have revolutionized cancer care. But not all patients respond, and scientists don’t fully understand why. Brendon Stiles, M.D., has received an Aspire Award from the Mark Foundation to investigate the potential benefits of blocking the enzyme ADP-ribosyltransferase 1(ART1), which is highly expressed on the cell surface of many non-small lung cancer tumors.

In previous research, Dr. Stiles found that ART1 blunts the body’s immune response against lung cancer. It does so by mono-ADP-ribosylating receptors on T cells and other immune cells, causing those cells to die. In work with mouse models of lung cancer, Dr. Stiles showed that inhibiting ART1 with a monoclonal antibody triggered an increase in immune cells that dramatically stopped the growth of lung cancer tumors. Now, Dr. Stiles will further explore the use of anti-ART1 monoclonal antibodies for treating lung cancer and assess whether the antibodies also help against other types of cancer. Dr. Stiles is assistant professor of cardiothoracic & vascular surgery at Einstein and associate director of surgical oncology at Albert Einstein Cancer Center.

Wednesday, September 01, 2021
 

Rewarding Research Recognition—Susan Band Horwitz, Ph.D., was recently honored by the Hope Funds for Cancer Research, which promotes research efforts in oncology and recognizes scientists, physicians, and philanthropists who have made a significant impact on patient outcomes through the award of an annual medal. The organization presented its medal to Dr. Horwitz for her outstanding contributions in cancer research, identifying the mechanism of action of chemotherapeutic drugs, particularly those derived from natural products, and evaluating drug resistance. Her most renowned work detailed the therapeutic properties of Taxol, which is widely used to treat numerous cancers and has saved millions of lives. Dr. Horwitz is distinguished professor emerita of molecular pharmacology and is the Rose C. Falkenstein Chair in Cancer Research. 

Tuesday, August 24, 2021
 

Elected to Serve—Robert H. Singer, Ph. D., was elected the Section 22 chair of the National Academy of Sciences (NAS). In this role, Dr. Singer oversees the election of new members to the NAS within cellular and developmental biology. The NAS is a prestigious nonprofit society of distinguished scholars whose members are elected in recognition of their outstanding achievements conducting original research. Dr. Singer’s election to the NAS in 2013 honored his exceptional accomplishments in cell biology, in particular his work with mRNA molecules and approaches to imaging RNA. He is professor and co-chair of anatomy & structural biology, professor in the Dominick P. Purpura Department of Neuroscience and of cell biology,  and co-director of the Gruss-Lipper Biophotonics Center and of the Integrated Imaging Program. He also holds the Harold and Muriel Block Chair in Anatomy & Structural Biology.

Thursday, August 12, 2021
 
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