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Julio A. Aguirre-Ghiso, Ph.D.

Julio A. Aguirre-Ghiso, Ph.D.

Professor, Cell Biology, Medicine and Oncology

Founding director, Cancer Dormancy and Tumor Microenvironment Institute

Co-Director, Gruss-Lipper Biophotonics Center

Co-Leader, Albert Einstein Cancer Center Tumor Microenvironment and Metastasis Program

Cancer biologyCancer dormancy and the tumor microenvironmentCancer metastasisStress signaling

Julio Aguirre-Ghiso, Ph.D., is an international leader in cancer cell dormancy and metastasis. He has helped lead a major shift in the cancer biology field by investigating how cancer cells hibernate, undetected, for long periods of time and what causes them to suddenly awaken to seed deadly, treatment-resistant metastases. read more...

 

Nir Barzilai, M.D.

Nir Barzilai, M.D.

Professor, Medicine (Endocrinology)

Director, Institute for Aging Research

Director, Nathan Shock Center of Excellence in the Basic Biology of Aging

Ingeborg and Ira Leon Rennert Chair of Aging Research

AgingBiology of agingLongevity genes

Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity. Dr. Barzilai has been profiled by major outlets, including The New York Times, PBS’ “NOVA scienceNow” and National Geographic. read more...

 

Ana Maria Cuervo, Ph.D., M.D.

Ana Maria Cuervo, Ph.D., M.D.

Professor, Developmental and Molecular Biology

Professor, Anatomy and Structural Biology

Co-Director, Institute for Aging Research

Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases

Molecular BiologyAgingAutophagy

Cellular biology

Dr. Cuervo is considered a leader in the field of autophagy— the process by which cells remove and recycle their waste. The Barcelona, Spain native is also an expert on the cellular biology of aging. Dr. Cuervo has been quoted in numerous publications, including The New York Times, Nature, Science, Scientific American, and The Scientistread more...

 

Liise-anne Pirofski, M.D.

Liise-anne Pirofski, M.D.

Professor, Medicine (Infectious Diseases), Einstein

Professor, Microbiology & Immunology, Einstein

Selma and Dr. Jacques Mitrani Chair in Biomedical Research, Einstein

Chief, Infectious Diseases, Department of Medicine, Einstein and Montefiore Health System

Infectious diseasesConvalescent plasmaCOVID-19PneumoniaImmunologyBacterial infections

A leading physician-scientist, Dr. Pirofski studies vaccine and antibody mediated immunity to infectious diseases, including cryptococcosis (the leading cause of fungal meningitis globally), pneumococcal pneumonia, and COVID-19. Her work has identified novel ways by which antibodies protect against pneumonia and the spread of fungal infections. She has spearheaded studies to understand the antibody response to the novel coronavirus, SARS-CoV-2.

Dr. Pirofski is co-author of the “damage-response framework of microbial pathogenesis,” a novel theory that incorporates the role of the host into the outcome of host-microbe interactions and infectious diseases.

As chief of the division of infectious diseases, Dr. Pirofski helped lead the Einstein and Montefiore response to the COVID-19 pandemic. She also co-authored a widely-cited commentary in the Journal of Clinical Investigation proposing the use of convalescent plasma as a potential treatment for COVID-19 and is leading Einstein and Montefiore’s participation in a randomized placebo-controlled clinical trial to test the efficacy of convalescent plasma in hospitalized patients.

Dr. Pirofski, who has been continuously funded by the National Institutes of Health throughout her career, is a member of the American Association of Physicians and a fellow of the American Academy of Microbiology, American College of Physicians, the Infectious Diseases Society of America, and the American Association for the Advancement of Science. She has received numerous awards for her accomplishments, including the Lifetime Achievement Award from the Albert Einstein College of Medicine Alumni Association and the American Society for Microbiology’s William A. Hinton Award, which honors outstanding contributions toward fostering the research training of underrepresented minorities in microbiology.