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  • Roee Holtzer, Ph.D.

Roee Holtzer, Ph.D.

Roee Holtzer

Professor, The Saul R. Korey Department of Neurology

Area of Research: Interests include: Neuropsychology, cognition, aging, dementia, neurodegenerative diseases, mobility, falls, rehabilitation.

Contact Information

718.430.3962718.839.7243Roee.Holtzer@einsteinmed.edu

Albert Einstein College of Medicine
1225 Morris Park Avenue
Van Etten, Room 311
Bronx, NY 10461

PubMed Portal

More Resources: Holtzer Lab

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Selected Publications

Select recent publications.*Denotes current or former students as co-authors

Holtzer, R., Choi, J., Motl, R., Foley, F.W., Picone, M.A., Lipton, M.L., Izzetoglu, M., Hernandez, M.E., Wagshul, M.E. (2023).   Individual reserve in aging and neurological disease.  Journal of Neurology. Mar 12:1-13. doi: 10.1007/s00415-023-11656-8. Online ahead of print.

*Brundage, K., Holtzer, R. (2023). Presence and Persistence of Perceived Subjective Cognitive Complaints and Incident Mild Cognitive Impairments Among Community-Residing Older Adults. The American Journal Geriatric Psychiatry. doi: 10.1016/j.jagp.2023.07.001. Online ahead of print.

*Ross, D., Wagshul, M.E.,Izzetoglu, M., Holtzer, R. (2023). Cortical Thickness Moderates Intraindividual Variability in Prefrontal Cortex Activation Patterns of Older Adults During Walking. Journal of the International Neuropsychological Society. doi: 10.1017/S1355617723000371. Online ahead of print.

*Jacobs, S., Izzetoglu, M., Holtzer, R. (2023).   The Impact of Music Making on Neural Efficiency & Dual-Task Walking Performance in Healthy Older Adults.  Aging Neuropsychology and Cognition. Mar 31:1-19. doi: 10.1080/13825585.2023.2195615. Online ahead of print.

*O’Brien, C., & Holtzer, R. (2023).   Physical reserve: construct development and predictive utility.  Aging Clinical and Experimental Research. doi: 10.1007/s40520-023-02371-5. Online ahead of print.

Wagshul, M.,, Foley, F.W., Chaudhary, K., Lipton, M.L., Robert Motl, R., Izzetoglu, M., Hernandez, M.E., Picone, M.A., & Holtzer, R., (2023).   Differential Associations of Mobility with Fronto-Striatal Integrity and Lesion Load in Older Adults with and without Multiple Sclerosis.  Neurorehabilitation and Neural Repair. Apr;37(4):205-217. doi: 10.1177/15459683231164787.

Holtzer, R., Zhu, X., Rosso, A. L., & Rosano, C. (2022). Cognitive reserve and risk of mobility impairment in older adults. J Am Geriatr Soc. 70(11), 3096-3104. doi:10.1111/jags.17979.

Holtzer, R., *Ross, D., *O'Brien, C., Izzetoglu, M., &. Wagshul, M. E. (2022). Cognitive Reserve Moderates the Efficiency of Prefrontal Cortex Activation Patterns of Gait in Older Adults. The journals of gerontology. Medical Sciences.  1;77(9):1836-1844]. doi: 10.1093/Gerona/glab288. 

*Kraut, R., & Holtzer, R. (2021). Recurrent but not single report of fear of falling predicts cognitive decline in community-residing older adults. Aging & mental health, 26(1), 100-106. doi: 10.1080/13607863.2021.1916878

*Pakray, H, Seng, E, Izzetoglu, M, Holtzer, R. (2021). The Effects of Perceived Pain in the Past Month on Prefrontal Cortex Activation Patterns Assessed During Cognitive and Motor Performances in Older Adults. Pain Med 2021;22:303-14. doi: 10.1093/pm/pnaa404.

*Holtzer, R., Ross, D., & Izzetoglu, M.  (2020). Intra-Individual-Variablity in Neural Activity in the Prefrontal Cortex During Active Walking in Older Adults. Psychology and Aging, 35(8), 12-01-1214.  Doi: 1037/pag0000583.

*Holtzer, R., Jacobs, S., & Demetriou, E. (2020). Intra-Individual Variability in Verbal Fluency Performance is Moderated by and Predictive of Mild Cognitive Impairments. Neuropschology. 34(1), 31-42.  doi: 10.1037/neu0000576. 

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In the News

More Media Coverage

  • How You Walk Could Flag Mental Decline

    The Wall Street Journal - August 31, 2017

    The research collaboration between Joe Verghese, M.B.B.S., and Roee Holtzer, Ph.D., has advanced our understanding of mobility and its link to cognition. Dr. Verghese is director of the Montefiore Einstein Center for the Aging Brain and Dr. Holtzer is professor of neurology at Einstein.

  • Thursday, April 18, 2013

    Several Einstein faculty members and their research are featured in a National Geographic cover story on the potential genetic roots of longevity.  Harry Ostrer, M.D., Roee Holtzer, Ph.D., and Nir Barzilai, M.D., are quoted, providing insight into the some likely genetic factors of healthy aging and the varied physiological and behavioral outcomes of these factors. Ongoing epigenetic investigations by Francine Einstein, M.D. and John Greally, M.B.B.Ch, Ph.D., are also highlighted, as is Dr. Holtzer’s collaborator Joe Verghese, M.B.B.S.

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