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W. Scott Melvin, M.D.

W. Scott Melvin, M.D.

Professor, Department of Surgery

Vice Chair, Department of Surgery Clinical Surgery at Montefiore Medical Center

Chief, Department of Surgery Division of Surgery at Montefiore Medical Center

Director, Department of Surgery Advanced Gastrointestinal Surgery at Montefiore Medical Center Moses & Weiler Divisions

Contact Information

718.920.4800718.798.1883wsmelvin@montefiore.org

Montefiore Medical Center
Medical Arts Pavilion
3400 Bainbridge Avenue
MMC-MAP, Room 4409
Bronx, NY 10467

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More Resources: General and Gastrointestinal Surgery

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Selected Publications

A. Original Communications in Reviewed Journals:

1. Baciewicz FA, Melvin WS, Basilius D, Davis JT: Congenital Heart Disease in Down's Syndrome Patients: A Decade of Surgical Experience. Thorac Cardiovasc Surgeon. 37: 369-371, 1989.

2. Melvin WS, Fitzpatrick JL: Injuries of the Thoracic Outlet. Seminars in Thoracic and Cardiovascular Surgery 4(3): 223-233. July 1992.

3. Melvin WS, Krasna MJ, McLaughlin JS: Thoracoscopic Management of Spontaneous Pneumothorax. Chest. 102: 1875-76. 1992.

4. Melvin WS, Wilkinson MA: Gastric Schwannoma, Clinical and Pathologic Considerations. American Surgeon. 59(5): 293-6. 1993.

5. Melvin WS, Burak WE, Flowers JL, Gann DS: Reno-colic Fistula: A Complication of Primary Repair of the Colon. Journal of Trauma. 35(6): 956-957. 1993.

6. Lefor AT, Melvin WS, Bailey RW, Flowers JL: Laparoscopic Splenectomy in the Management of Immune Thrombocytopenia Purpura. Surgery. 114(3): 613-8. 1993.

7. Melvin WS, Johnson JA, Sparks J, Innes JT, Ellison EC: Long-term prognosis of Zollinger-Ellison Syndrome in Multiple Endocrine Neoplasia. Surgery. 114(6): 1183-8. 1993.

8. Brusko G, Melvin WS, Fromkes J, Ellison EC. Pancreatic Tuberculosis. American Surgeon. 61(6): 513-15. 1995

9. Schirmer WJ, Melvin WS, Rush RM, O'Dorisio TM, Pozderac RV, Olsen JO, Ellison EC: Indium Pentatreotide Scanning versus Conventional Imaging Techniques for the Localization of Gastrinoma. Surgery. 188(6): 1105-1110. 1995.

10. Behrman SW, Melvin WS, Babb EM, Johnson JA, Ellison EC. Laparoscopic Cholecystectomy in the Geriatric Population. American Surgeon. 62(5): 386-390, 1996.

11. Miller CA, Melvin WS: Duodenocaval Fistula Complicating Peptic Ulcer Disease: Case Report and Review of the Literature. Surgery. 119(6): 718-719. 1996.

12. Behrman SW, Melvin WS, Ellison EC. Pancreatic Pseudocysts Following Acute Pancreatitis. American Journal of Surgery, 172(3): 228-231.1996.

13. Melvin WS, Johnson JA, Ellison EC: Laparoscopic Skills Enhancement. American Journal of Surgery. 172(4): 377-379, 1996.

14. Bakalakos ET, Kirkpatrick RF, Melvin WS. Liver Abscess Secondary to Intrahepatic Perforation of the Gallbladder, Presenting as a Liver Mass. American Journal of Gastroenterology. 91(8): 1644-46, 1996.

15. Melvin WS: Laparoscopic Resection of a Pelvic Schwannoma. Surgical Laparoscopy & Endoscopy. 6(6): 489-491, 1996.

16. Melvin WS, Bumgardner GL, Davies EA, Elkhammas EA, Henry ML, Ferguson RM. The Laparoscopic Management of Post-transplant Lymphoceles: A Critical Review. Surgical Endoscopy. 11:245-248, 1997.

17. Miller CA, Melvin WS, Schirmer WJ, Johnson JA, Sparks J, Ellison EC. Preoperative Serum Gastrin Level: A Prognostic Indicator in Metastatic Gastrinoma. Current Surgery, 54(2): 102-106,1997.

18. Melvin WS, Boros LG, Muscarella P, Brandes JL, Johnson JA, Schirmer WJ, Ellison EC. Dehydroepiandrosterone Sulfate Inhibits Pancreatic Cancer Growth In vitro and In vivo. Surgery, 121(4): 392-397, 1997.

19. Boros LG, Puigjaner J, Cascante M, Lee PWN, Brandes, Bassilian S, Yusuf FI, Williams RD, Muscarella P, Melvin WS, Schirmer WJ. Oxythiamine and Dehydroepiandrosterone Inhibit the Non Oxidative Synthesis of Ribose and Tumor Cell Proliferation. Cancer Research. 57(19): 4242-4248,1997.

20. Skarda JA, Melvin WS. Current Management of Acute Pancreatitis. Medical Update for Psychiatrists. 2(5): 138-144, November, 1997.

21. Ikramuddin S, Melvin WS. Chronic Pancreatitis: Current Diagnosis and Treatment. Medical Update for Psychiatrists. 3(1): 1-6, December, 1997.

22. Boros LG, Brandes JL, Puigjaner J, Revesv E, Bray TM, Lee P, Cascante M, Muscarella P, Schirmer WJ, Melvin WS. Thiamine Supplementation to Cancer Patients: A Double Edged Sword. Anticancer Research. 18(1B): 595-602, 1998.

23. Muscarella P, Melvin WS, Fisher WE, Foor J, Ellison EC, Herman JG, Schirmer WJ, Hitchcock CL, DeYoung BR, Weghorst CM. Genetic Alterations in Gastrinomas and Nonfunctioning Pancreatic Neuroendocrine Tumors: An Analysis of p16/MTS1 Tumor Suppressor Gene Inactivation. Cancer Research, 58: 237-240, January, 1998.

24. Melvin WS, Beukers KA, Johnson JA, Schirmer WS, Babb ME, Muscarella P, Ellison EC: Outcome Analysis of Long-Term Survivors Following Pancreaticoduodenectomy. Journal of Gastrointestinal Surgery, 2(1):72-78, 1998.

25. Boros LG, Lee P, Brandes JL,Cascante M, Muscarella P, Schirmer WJ, Melvin WS, Ellison EC. Non-Oxidative Pentose Phosphate Pathways and their Direct Role in Ribose Synthesis in Tumors: Is Cancer a Disease of Cellular Glucose Metabolism? Medical Hypothesis, 50: 55-59, 1998.

26. Melvin WS, Meier DJ, Elkhammas EA, Bumgardner GL, Davies EA, Henry ML, Pelletier R Ferguson RM. Prophylactic Cholecystectomy is not Indicated Following Renal Transplantation. American Journal of Surgery. 175:317-319, 1998.

27. Muscarella P, Boros LG, Fisher WE, Brandes JL, Rink C, Ellison EC, Johnson JA, Melvin WS. Dehydroepiandrosterone Inhibits the Growth of Human Pancreatic Cancer Cells in Nude Mice. Journal of Surgical Research 79: 154-157, October, 1998.

28. Ikramuddin S, Lucas J, Schirmer WS, Ellison EC, Melvin WS. Cellular Aerosolization During Laparoscopy. Journal of Gastrointestinal Surgery, 2(6): 581-584, November, 1998.

29.Cook CH, Melvin WS, Groner J, Allen E, King DR. A Cost Effective Thoracoscopic Treatment Strategy for Pediatric Spontaneous Pneumothorax. Surgical Endoscopy, 13(12): 1208-1210. December, 1999.

30. Damore LJ, Melvin WS. SurgicalTechnique of Appendectomy by Laparotomy and Laparoscopy. Operative Techniques in Gynecologic Surgery, Vol 4, No 4, 1999: 215-220.

31.Damore LJ, Johnson JA, Dixon RS, Iverson MA, Ellison EC, Melvin WS. Transmission of Live Laparoscopic Surgery over the Internet 2. American Journal of Surgery, 178:415-417, 1999.

32. Damore LJ, Melvin WS. Laparoscopic Postmortem Examination: A Minimally Invasive Approach to the Autopsy. Annals of Diagnostic Pathology, 4(2): 95-98, 2000.

33. Damore LJ, Fernandez K, Cook CH, Cunningham J, Melvin WS, Ellison EC. Ultrasonography Incorrectly Diagnoses Gallbladder Polyps. Surgical Laparoscopy Endoscopy and Percutaneous Techniques, 11(2): 88-91, 2001.

34. CH Cook, PA Muscarella, AC Praba, WS Melvin, LC Martin. Reducing Over-Triage Without Compromising Outcomes in Trauma Patients, Archives of Surgery 136(7): 752-756, 2001.

35.Muscarella P, Knobloch TJ, Ulrich AB, Casto BC, Moniaux N, Wittel UA, Melvin WS, Pour PM, Song H, Gold H, Batra SK, Weghorst CM. Identification and sequencing of the Syrian Golden Hamster (Mesocricetus auratus) p16^INK4a and p15^INK4b cDNAs and their Homozygous Gene Deletion in Cheek Pouch and Pancreatic Tumor Cell Lines. Gene, Oct 31;278 (1-2):235-43, 2001.

36. Melvin WS, Needleman BJ, Krause KR, Schneider C, Ellison EC. Computer–Enhanced versus Standard Laparoscopic Antireflux Surgery. Journal of Gastrointestinal Surgery 6(1): 11-16. 2002.

37. Gould JC, Melvin WS. Computer Assisted “Robotic” Antireflux Surgery. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 12(1): 26-29, 2002.

38. Melvin WS, Krause KR, Needleman BJ, Wolf RW, Ellison EC. Computer Assisted “Robotic” Heller Myotomy: Initial Case Report. J Laparoendosc Adv Surg Tech A. 2001 Aug;11(4):251-3

39.Melvin WS, Krause KR, Needleman BJ, Wolf RK, Michler RM, Ellison EC. Computer Assisted “Robotic” Foregut Surgery, Initial Experience in North America. Surgical Endoscopy 16(12): 1790-1792, 2002

40. Gould JC, Needleman BJ, Ellison EC, Muscarella P, Schneider C, Melvin WS. Evolution of Minimally Invasive Bariatric Surgery. Surgery 132: 565-72, 2002.

41. Melvin WS, Krause KR, Needleman BJ, Ellison EC. “Robotic” Resection of A Pancreatic Neuroendocrine Tumor. Journal of Laparoendoscopic & Advanced Surgical Techniques 13(1):33-36, 2003.

42. Li J, Qin D, Knobloch TJ, Tsai M, Weghorst CM, Melvin WS and Muscarella P. Expression and Characterization of Syrian Golden Hamster p16, a Homologue of Human Tumor Suppressor p16^INK4A. Biochem Bioph Res Com. 2003; 304:241-247.

43. Melvin WS. Robots in Surgery: Advanced Gastrointestinal Applications and Credentialing. Journal of Gastrointestinal Surgery. 2003; (4): 481-483.

44. Talamini M, Chapman WC, Horgan S, Melvin WS. Evaluation of 211 “Robotic” Surgical Procedures. Surgical Endoscopy, 2003; 17: 1521-1524.

45. Gould JC , Melvin WS. Telerobotic Foregut and Esophageal Surgery. Surg Clin N Am. 83(2003), 1421-1427.

46. Strayer MP, Krause KR, Dalstrom DJ, Stover EA, Cook CH, Needleman BJ, Melvin WS. Computer Enhanced Robotic Telesurgery versus Standard Laparoscopy: Training Improves Performance on Skills Testing. In Press, Surgical Endoscopy, February, 2003.

47. Go MR, Muscarella P, Needleman BJ, Cook CH, Melvin WS. Endoscopic Management of Stomal Stenosis after Roux-en-Y Gastric Bypass. Surg Endosc. 2004 Jan;18(1):56-9. Epub 2003 Nov 21.

48. Melvin WS. Minimally Invasive Pancreatic Surgery. Am Journal of Surgery 186:274-278, 2003.

49. Li J, Weghorst CM, Tsutsumi M, Poi MJ, Knobloch TJ, Casto BC, Melvin WS, Tsai M, and Muscarella P. Frequent p16^INK4A/CDKN2A Alterations in Chemically Induced Syrian Golden Hamster Pancreatic Tumors. Carcinogenesis. 2003; 25(1):1-6.

50. Mcgrath V, Needleman BJ, Melvin WS. Evolution of Minimally Invasive Bariatric Surgery. J Laparoendosc Adv Surg Tech A. 2003 Aug;13(4):221-7.

51. McGrath V, Melvin WS. Robotic Surgery in the Treatment of Gastroesophageal Reflux Disease. Problems in General Surgery 20(2):38-45, 2003.

52. Li J, Melvin WS, Tsai MD, and Muscarella P. The Nuclear Protein p34SEI-1 Regulates the Kinase Activity of Cyclin-Dependent Kinase 4 in a Concentration-Dependent Manner.

Biochemistry 2004, 43, 4394-4399.

53. Roy S, Clark CJ, Mohebali K, Bhatt U, Wallace WA, Nahman S, Ellison EC, Melvin WS and Sen CK. Reactive Oxygen Species and EGR-1 Gene Expression in Surgical Postoperative Peritoneal Adhesions. World J Surg. 2004 Mar;28(3):316-20. Epub 2004 Feb 17

54. Melvin WS. Roux en Y Gastric Bypass is the Operation of Choice for Obesity. Journal of Gastrointestinal Surgery. 2004 8(4): 398-400.

55. Newlin ME, Melvin WS. Initial experience with the four-arm computer-enhanced

telesurgery device in foregut surgery. J of Adv Laparoendosc Advanced Surg Tech 2004; 14, 121-124.

56. Go MR, Dundon JM, Karlowicz DJ, Domingo C, Muscarella P, Melvin WS. Delivery of Radiofrequency Energy to the Lower Esophageal Sphincter (Stretta) Improves Symptoms of GERD. Surgery. 2004 Oct;136(4):786-94.

57. Wright AS, Gould JC, MelvinWS. Computer-assisted robotic antireflux surgery. Minerva Gastroenterol Dietol 2004; 50: 253-60.

58. Hazey J, Melvin WS. Robot-assisted General Surgery. Semin Laparosocpic Surgery. Jun;11(2):107-12. 2004.

59. Fries RB, Wallace WA, Roy S, Kuppusamy P, Bergdall V, Gordillo GA, Melvin WS, Sen CK. Dermal Excisional Wound Healing in Pigs Following Treatments with Topically Applied Pure Oxygen. Mutat Res. 2005 Nov 11;579(1-2):172-81. Epub 2005 Aug 18.

60. Davis SS Jr., Mikami DJ, Needleman B, Larson T, Dundon J, Fries R, Barret M, Newlin M, Goldblatt MI, Melvin WS. Heating and Humidifying of Carbon Dioxide During Pneumoperitoneum is not Indicated: A Prospective Randomized Trial. Surgical Endoscopy(2006) 20: 153-158.

61. Ergun K, Ober J, Berme N, Melvin WS. Eye Motion Paramaters Correlate with Level of Experience in Video-Assisted Surgery: Objective Testing of Three Tasks. Journal of Laparoendoscopic & Advanced Surgical Techniques. 2005 Dec;15(6)

62. Melvin WS, Dundon JM, Talamini MA, Horgan S. Computer Enhanced Robotic Telesurgery Reduces Esophageal Perforation During Heller Myotomy. Surgery. 2005 Oct;138(4):553-8; discussion 558-9.

63. Melvin WS. Invited Commentary, On: Robotic Splenectomy. World J Surg. 2005 Jun 30; [Epub ahead of print].

64. Li J, Muscarella P, Joo SH , Knobloch J, Melvin WS, Weghorst CM, Tsai MD. Dissection of CDK4-Binding and Transactivation Activities of p34SEI-1 and Comparison between Functions of p34SEI-1 and p16INK4A. Biochemistry. 2005 Oct 11;44(40):13246-13256

65. Tempero MA, Behrman S, Ben-Josef E, Benson AB 3rd, Cameron JL, Casper ES, Hoffman JP, Karl RC, Kim P, Koh WJ, Kuvshinoff BW 2nd, Melvin WS, Muscarella P 2nd, Sasson AR, Shibata S, Shrieve DC, Talamonti MS, Tyler DS, Vickers SM, Warren RS, Willett C, Wolff RA; National Comprehensive Cancer Network. Pancreatic adenocarcinoma: Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2005 Sep;3(5):598-626.

66.Dunkin BJ, Martinez J, Bejerano P, Smith CD, Chang K, Livingstone AS, Melvin WS. Thin-Layer Ablation of Human Esophageal Epithelium Using a Bipolar Radiofrequency Balloon Device. Surg Endosc (2006) 20: 125-130.

67. Li J, Zhu J, Melvin WS, Bekaii-Saab TS, Chen CS, and Muscarella P. A Structurally Optimized Celecoxib Derivative Inhibits Human Pancreatic Cancer Cell Growth. J Gastrointest Surg. 2006 Feb;10(2):207-214.

68. Davis SS Jr., Goldblatt MI, Hazey JW, Melvin WS. Unexpected gastrointestinal tract conditions. Curr Probl Surg. 2006 Feb; 43(2):77-118

69. Ellison EC, Sparks J, Verducci JS, Johnson JA, Muscarella P, Melvin WS. Fifty-Year Appraisal of Gastrinoma: Recommendations for Staging and Treatment. J Am Coll Surg 2006; 202:897-905.

70. Smith CD, Bejarno P, Melvin WS, Patti M, Muthusamy R, Dunkin BJ. Endoscopic Ablation of Intestinal Metaplasia Containing High-Grade Dysplasia in Esophagectomy Patients Using a Balloon-Based Ablation System. Surg Endosc. 2007 Apr;21(4):560-9. Epub 2006 Dec 16.2006 Dec 16;

71. Hazey JW, McCreary M, Guy G, Melvin WS. Efficacy of Percutaneous Treatment of Biliary Tract Calculi using the Holmium-YAG Laser. Surg Endosc. 2007 Jul;21(7):1180-3. Epub 2007 Feb 8.

72. Hazey JW, Dunkin BJ, Melvin WS. Changing Attitudes Toward Endoluminal Therapy. Surg Endosc. 2007 Mar;21(3):445-8.

73. Bloomston M, Ellison EC, Muscarella P, Al-Saif O, Martin EW, Melvin WS, Frankel WL.

Stromal osteonectin overexpression is associated with poor outcome in patients with ampullary cancer. Ann Surg Oncol. 2007 Jan;14(1):211-7.

74. Bloomstom M, Bekaii-Saab TS, Kosuri K, Cowgill SM, Ellison EC, Melvin WS, Muscarella P. Preoperative carbohydrate antigen 19-9 is most predictive of malignancy in older jaundiced patients undergoing pancreatic resection. Pancreas. 2006 Oct;33(3):246-9.

75. Zervos EE, Tanner SM, Osborne DA, Bloomston M, Rosemurgy AS, Ellison EC, Melvin WS, de la Chappelle A. Differential gene expression in patients genetically predisposed to pancreatic cancer.
J Surg Res. 2006 Oct;135(2):317-22. Epub 2006 Jun 30.

76. Narula VK, Patel V, Hazey JW, Mikami D, Watson WC, Needleman BJ, Hinshaw K, Melvin WS. A Computerized Analysis of Robotic versus Laparoscopic Task Performance. Surg Endosc 2007 Dec; 21(12): 2258-61.

77. Reavis KR, Renton D, Melvin WS. Robotic Telesurgery for Achalasia. Journal of Robotic Surgery, (2007) 1:25-30.

78. McGuire L, Heffner K, Glaser R, Needleman BJ, Malarkey W, Dickinson S, Lemeshow S, Cook CH, Muscarella P, Melvin WS, Ellison EC, Kiecolt-Glaser JK. Pain and wound healing in surgical patients. Ann Behav Med. 2006 Apr; 31(2):165-72.

79. Emery CF, Fondow MDM, Schneider CM, Christofo FL, Hunt C, Busby AK, Needleman BJ, Melvin WS, Elsayed-Awad HM. Gastric bypass surgery is associated with reduced inflammation and less depression: A preliminary investigation. Obes Surg. 2007 Jun;17(6):759-63.

80. Hazey JW, Narula VK, Renton DR, Reavis DR, Paul CM , Hinshaw KE, Muscarella P, Ellison EC, Melvin WS. Natural Orifice Translumenal Endoscopic Surgery in Humans: Initial Clinical Trial. Surgical Endoscopy, 2008 Jan; 22(1): 16-20. Epub 2007, Aug 14.

81. Cios TJ, Reavis KR, Renton DR, Hazey JW, Mikami DJ, Allemang MT, Davis SS, Melvin WS. Gastrotomy Closure Using Bioabsorbable Plugs in a Canine Model, Surg Endosc. 2008 Apr;22(4):961-6. Epub 2007 Aug 19.

82. Narula VK, Hazey JW, Reavis KR, Renton DR, Paul CM, Hinshaw KE, Needleman BJ, Mikami DJ, Ellison EC, Melvin WS. Transgastric Instrumentation and Bacterial Contamination of the Peritoneal Cavity. Surg Endosc. 2008 Mar;22(3):605-11. Epub 2007 Nov 20.

83. Bergman S, MelvinWS. Operative and Nonperative Management of Pancreatic Pseudocysts. Surg Clin N Am 87 (2007); 1447-1460.

84. Wunderlich JE, Needelman BJ, Chen Z, Yu JG, Wang YZ, Grants I, Mikami D, Melvin WS, Cooke HJ, Christofi FL. Dual Purinergic Synaptic Transmission in the Human Enteric Nervous System. Am J Physiol Gastrointest Liver Physiol. 2008 Feb;294(2):G554-66. Epub 2007 Dec 13.

85. Reavis KM, Melvin WS. Advanced Endoscopic Technology. Surg Endosc. Surg Endosc. 2008 Jun;22(6):1533-46. Epub 2008 Apr 10. Review

86. Narula VK, Happel , Bergman S, Roland JC, Melvin WS, Hazey JW. Transgastric Endoscopic Peritoneoscopy Does Not Require Decontamination of the Stomach in Humans. In Press, Surgical Endoscopy, April, 2008.

87. Bergman S, Fix DJ, Volt K, Roland JC, Happel L, Reavis KM, Cios TJ, Ho V, Evans A, Narula VK, Hazey JW, Melvin WS. Do Gastrostomies Require Repair after Transgastric Peritoneoscopy: A Controlled Trial. Gastrointestinal Endoscopy, 71 (2010), pp. 1013-1017.

88. Bergman, S, Mikami, DJ, Hazey, JW, Roland, JC, Dettorre, BA, Melvin, WS. Endolumenal Fundoplication With EsophyX: The Initial North American Experience. Surgical Innovation, (2008) 15: 3 166-70.

89. Bergman S, Melvin WS. Natural Orifice Translumenal Endoscopic Surgery. Surg Clin North Am. 2008 Oct;88 (5):1131-1148.

90.Herron DM, Marohn M, Melvin WS (The SAGES-MIRA Robotic Surgery Consensus Group) A Consensus Document on Robotic Surgery. Surg Endosc (2008) 22:313-325.

91. Narula VK, Mikami D, Melvin WS. Robotic and Laparoscopic Pancreaticoduodenectomy, Initial Experience with a Hybrid Technique. Pancreas, March 1, 2010. 39(2).

92. Dundon JM, Muscarella P, Narula VK, Davis SS, Melvin WS. Long term Follow up Radiofrequency Energy Delivery to the Gastroesophageal Junction for the Treatment of GERD. Surgical Innovation, 2008 Dec;15(4):297-301.

93. Melvin WS, Narula VK, Hill J, Lehr A, Davis SS, Reavis, KM, Muscarella P and the Columbus Surgical Society. Surgical Management of Appendicitis: 50 Years of Progress? Submitted, 2008.

94. Mikami D, Needleman BJ, Narula VK, Durant J, Melvin WS. Natural Orifice Surgery: Initial US Experience Utilizing the Stomaphyx Device to Reduce Gastric Pouches after Roux en Y Gastric Bypass. Surg Endosc. 2009 Jul 25. ePub ahead of Print.

95. Dillhof M, Yates R, Wall K, Muscarella P, Melvin WS, Ellison EC, Bloomston M Intraoperative Assessment of Pancreatic Neck Margins at the Time of Pancreaticoduodenectomy increases likelihood of Margin negative resection in patients with Pancreatic Cancer. J Gastrointest Surg, 2009 Mar 10 (ePub ahead of Print)

96. Bloomston M, Kneile J, Butterfield M, Dillhoff M, Muscarella P, Ellison EC, Melvin WS, Croce CM, Pichiorri F, Huebner K and Frankel WL. Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features. Ann Surg Oncol. 2009 Aug;16(8):2331-8.

97. Demyttenaere SV, Bergman S, Pham T, Anderson J, Dettorre R, Melvin WS, Mikami DJ Transoral incisionless fundoplication for gastroesophageal reflux disease in an unselected patient population. Surg Endoscop: Volume 24, Issue 4 (2010), Page 854. Epub ahead of Print Sep 3, 2009.

98. Demyttenaere SV, Nau P, Henn M, Beck C, Zaruby J, Primavera M, Kirsch D, Miller J, Liu JJ, Bellizzi A, Melvin WS. Barbed Suture for Gastrointestinal Closure: A Randomized Control Trial. Surgical Innovation. 2009. 16 (3):237-242.

99. Narula VK, Mikami DJ, Melvin WS. Robotic and laparoscopic pancreaticoduodenectomy: a hybrid approach. Pancreas. 2010 Mar;39(2):160-4.

100. Nau P, Demyttenaere S, Muscarella P, Narula V, Hazey JW, Ellison EC, Melvin WS. Pheochromocytoma does not increase risk in laparoscopic adrenalectomy. Surg Endosc. 2010 Nov;24(11):2760-4. Epub 2010 Apr 8.

101.Nau P, Ellison EC, Muscarella P Jr, Mikami D, Narula VK, Needleman B, Melvin WS, Hazey JW. A review of 130 humans enrolled in a transgastric NOTES protocols at a single institution. Surg Endosc. 2011 Apr;25(4):1004-11. Epub 2010 Oct 26. Review.

102.Abdel-Misih SR, Hatzaras I, Schmidt C, Saab TB, Klemanski D, Muscarella P, Melvin WS, Ellison EC, Bloomston M. Failure of normalization of CA19-9 following resection for pancreatic cancer is tantamount to metastatic disease. Ann Surg Oncol. 2011 Apr;18(4):1116-21. Epub 2010 Nov 2.

103.Sun X, Wang X, Wang GD, Xia Y, Liu S, Qu M, Needleman BJ, Mikami DJ, Melvin WS, Bohn LM, Ueno R, Wood JD. Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine. Dig Dis Sci. 2011 Feb;56(2):330-8. Epub 2010 Dec 23.

104.Nau P, Anderson J, Yuh B, Muscarella P Jr, Christopher Ellison E, Happel L, Narula VK, Melvin WS, Hazey JW. Diagnostic Transgastric Peritoneoscopy, extension of intial human trial for staging pancreatic head masses. Surg Endosc. 2010 Jun;24(6):1440-6. Epub 2010 Jan 7.

105. Nau P, Anderson J, Needleman B, Ellison EC, Melvin WS, Hazey JW. Endoscopic transgastric insufflation and access: natural orifice translumenal endoscopic surgery. Gastrointest Endosc. 2010 Mar;71(3):485-9. Epub 2009 Dec 8.

106.Hatzaras I, Schmidt C, Klemanski D, Muscarella P, Melvin WS, Ellison EC, Bloomston M. Pancreatic Resection in the octogenarian: a safe option for pancreatic malignancy. J Am Coll Surg. 2011 Mar;212(3):373-7. Epub 2011 Jan 12.

107. Shah NR, Mikami DJ, Cook C, Manilchuk A, Hodges C, Memark VR, Volckmann ET, Hall CR, Steinberg S, Needleman B, Hazey JW, Melvin WS, Narula VK. A comparison of outcomes between open and laparoscopic surgical repair of recurrent inguinal hernias. Surg Endosc. 2011 Jul;25(7):2330-7. Epub 2011 Feb 7.

108. Memark VC, Anderson JB, Nau PN, Shah N, Needleman BJ, Mikami DJ, Melvin WS, Hazey JW. Transgastric endoscopic peritoneoscopy does not lead to increased risk of infectious complications. Surg Endosc. 2011 Jul;25(7):2186-91. Epub 2011 Feb 7.

109. Melvin WS, Renton D. Laparoscopic Ventral Hernia Repair. World J Surg. 2011 Jul;35(7):1496-9.

110. Melvin WS. Modern Treatment for Gastroesophageal Reflux Disease: Surgery vs Medication. Arch Surg. 2011 Sep;146(9):1093-4.

111.Nau P, Liu J, Ellison EC, Hazey JW, Henn M, Muscarella P, Narula VK, Melvin WS. Novel Reconstruction of the extrahepatic biliary tree with a biosynthetic graft. HPB (Oxford). 2011 Aug;13(8):573-8. doi: 10.1111/j.1477-2574.2011.00337.x. Epub 2011 Jun 27.

112. Nau P, Melvin WS, Narula VK, Bloomston M, Ellison EC, Muscarella P. Laparoscopic distal pancreatectomy with splenic conservation: An operation without increased morbidity. Gastroenterology Research and Practice., Volume 2009, Article ID 846340.

113. Hatzaras I, George N Predictors in survival in Periampullary cancers following Pancreaticoduodenectomy. Ann Surg Oncol. 2010 Apr;17(4):991-7. Epub 2010 Jan 28

114. Rattner DW, Hawes RH, Schwaitzberg S, Kochman ML, Swanstrom L, and the Joint Committee on Natural Orifice Transluminal Endoscopic Surgery (Ginsberg GG, Gostout CJ, Marohn M, Melvin WS, Rothstein R, Scott DJ, Talamini M, ThompsonCC.) The 2^nd ASGE/SAGES White Paper on Natural Orifice Translumenal Endoscopic Surgery – Five Years of Progress. Surg Endosc, 2011.

115. Qin R, Melvin WS, Xu RX. Benchtop Validation of Contrast Enhanced Ultrasound and Fluorescence Imaging in Video Guided Cholecystectomy. Submitted, Journal of Biomedical Optics. Dec. 2010.116.

116. Qin R, Melvin WS, MelvinWJ, Xu RX. Indocyanine Green loaded Microballoons for Biliary imaging in Cholecystectomy. Opt. 17 (11), 116025 (November 19, 2012); doi:

10.1117/1.JBO.17.11.116025

117. Meyerson JM, Noria S, Melvin WS. A retained foreign body mimicking Cancer. Surg Laparosc Endosc Percutan Tech. 2012 Aug;22(4):e220-1

118. Hazey JW, Marks JM, Mellinger JD, Melvin WS. Why FES? The fundamentals of Endoscopic Surgery Taskforce Report. Surg Endosc. 2014 Mar;28(3):701-3.

119. Wendling MR, Linn JG, Keplinger KM, Mikami DJ, Perry KA, Melvin WS, Needleman BJ.Omental patch repair effectively treats perforated marginal ulcer following Roux-en-Y gastric bypass. Surg Endosc. 2013 Feb;27(2):384-9

120. Schumer E, Perry K, Melvin WS.Minimally invasive esophagectomy for esophageal cancer: evolution and review.Surg Laparosc Endosc Percutan Tech. 2012 Oct;22(5):383-6

121. Perry KA, Banarjee A, Liu J, Shah N, Wendling MR, Melvin WS.

Gastric ischemic conditioning increases neovascularization and reduces inflammation and fibrosis during gastroesophageal anastomotic healing. Surg Endosc. 2013 Mar;27(3):753-60

122.Ganz RA, Peters JH, Horgan S, Bemelman WA, Dunst CM, Edmundowicz SA, Lipham JC, Luketich JD, Melvin WS .Esophageal sphincter device for gastroesophageal reflux disease. Engl J Med. 2013 Feb 21;368 (8):719-27

123. Perry KA, Linn JG, Eakin JL, Onders RP, Velanovich V, Melvin WS. Transoral incisionless fundoplication does not significantly increase morbidity of subsequent laparoscopic Nissen fundoplication. J Laparoendosc Adv Surg Tech A. 2013 May;23(5):456-8.

124.Wendling MR, Melvin WS, Perry KA.Impact of transoral incisionless fundoplication (TIF) on subjective and objective GERD indices: a systematic review of the published literature.

Surg Endosc. 2013 Oct;27(10):3754-61.

125.Matthews JB, Melvin WS.Current Concepts and Controversies in Foregut Motility: the 2012 Kelly and Carlos Pellegrini SSAT/SAGES Joint Symposium. J Gastrointest Surg. 2013 Sep;17(9):1545-6

126.Funk LM, Perry KA, Narula VK, Mikami DJ, Melvin WS.Current national practice patterns for inpatient management of ventral abdominal wall hernia in the United States. Surg Endosc. 2013 Nov;27(11):4104-12

127.Perry KA, Funk LM, Muscarella P, Melvin WS. Perioperative outcomes of laparoscopic transhiatal esophagectomy with antegrade esophageal inversion for high-grade dysplasia and invasive esophageal cancer. Surgery. 2013 Oct;154(4):901-7; discussion 907-8.

128.Perry KA, Walker JP, Salazar M, Suzo A, Hazey JW, Melvin WS. Endoscopic management of high-grade dysplasia and intramucosal carcinoma: experience in a large academic medical center. Surg Endosc. 2014 Mar;28(3):777-82.

129.Collins A, Hatzaras I, Schmidt C, Carruthers K, Melvin WS, Muscarella P, Ellison EC, Martin E, Bloomston M. Gastrectomy in advanced gastric cancer effectively palliates symptoms and may improve survival in select patients. J Gastrointest Surg. 2014 Mar;18(3):491-6.

130.Hazey JW, Marks JM, Mellinger JD, Trus TL, Chand B, Delaney CP, Dunkin BJ, Fanelli RD, Fried GM, Martinez JM, Pearl JP, Poulose BK, Sillin LF, Vassiliou MC, Melvin WS.

Why fundamentals of endoscopic surgery (FES)? Surg Endosc. 2014 Mar;28(3):701-3.

B. Books, Chapters in Books, and Review Articles:

1. Melvin WS, Ellison EC: Pancreatitis in Pregnancy. Current Therapy in Obstetrics and Gynecology. ed Zuspan FP and Quilligan T. 4th Ed. Mosby Year Book. 268-272. 1994.

2. Melvin WS, Ellison EC: Endoscopic Procedures for the Gastrointestinal Tract. Ambulatory Anesthesia and Surgery, ed. White PF. W. B. Saunders. 265-270. 1996.

3. Ellison EC, Melvin WS, Moon SG: Current Applications of Lateral Choledochoduodenostomy and Transduodenal Sphincteroplasty. Mastery of Surgery, ed. Nyhus LM, Baker RJ, Fischer JE.Third Edition, Little-Brown, Boston. 1118-1126, 1996.

4. Melvin WS, Flowers JL: Laparoscopic Surgery of Solid Organs: Liver, Spleen and Adrenal Gland. Resident Training Manual, Society of Gastrointestinal and Endoscopic Surgeons, December,1995.

5. Melvin WS, Ellison EC: Pancreatitis in Pregnancy. Current Therapy in Obstetrics and Gynecology. ed Zuspan FP and Quilligan T. 5th Ed. Mosby Year Book. 269-273. 1998.

6. Muscarella P, Fisher W, Johnson JA, Melvin WS. Neoplastic Disorders of the Pancreas. Clinical Pathology of Pancreatic Disorders, ed. Lott JA. Humana Press, 125-162, 1997.

7.Damore LJ II, Melvin WS. Surgical Technique of Appendectomy. Operative Techniques in Gynecologic Surgery, ed. Hewitt G, Gershenson DM.Vol. 4, (4). W.B.Saunders Co., 215-220, 1999.

8. Melvin WS. Hand Assisted Roux-en-Y Gastric Bypass. Atlas of Hand Assisted Laparoscopic Surgery. ed. Gerhart CD. First Edition, 23-27. 2000.

9. White LM, Roy S, Gordillo GM, Kallianene LK, Melvin WS, Ellison EC, Sen CK. Wound Healing and Regeneration, in Physiology and Maintenance, edited by Osmo Hanninen, in Encyclopedia of Life Support Systems (EOLSS), Eolss Publishers, Oxford, UK, [http://www.eolss.net]

10. Ellison EC, Melvin WS, Moon S.Current Applications of Lateral Choledochoduodensotomy and Transduodenal Sphinteroplasty. Mastery of Surgery. Ed. Baker RJ, Fischer JE. 4^th edition, Lippincott Williams & Wilkins. Philadephia. p1171-1181, 2001

11. Hazey JW, Melvin WS. Robot Assisted General Surgery. Seminars in Laparoscopic Surgery. Ed Anvari M and Park AE. 11:2; June 2004. 107-113.

12.Kirakopolous A, Melvin WS. Robotics in Surgery in The SAGES Manual: Fundamentals of Laparoscopy and GI Endoscopy, 2^nd ed. Editor Scott-Connnor CEH. Springer-Verlag, NY. pp 96-106.

13. Gould JC and Melvin WS. Robotics in Endoscopic and Laparoscopic Surgery. In Mastery of Endoscopic and Laparoscopic Surgery, 2ed. Editors. Soper N, Swanstrom L, Eubanks WS. Lipincott, Williams & Wilkins, Philadelphia. pp130-137, 2005.

14. Melvin WS and Goldblatt MI. Prevention and Management of Complications in
Minimally Invasive Esophageal Surgery. In Prevention and Management of Complications in Laparoendoscopic Surgery. 2^nd ed. Editors, Wetter PA, Kavic MS, Levinson CJ and Kelley W. pp157-163, 2005.

15. Davis SS and Melvin WS. Laparoscopic Pancreatic Surgery. In Prevention and Management of Complications in Laparoendoscopic Surgery. 2^nd ed. Editors, Wetter PA, Kavic MS, Levinson CJ and Kelley W.pp 309-315, 2005.

16. Newlin M and Melvin WS. Laparoscopic Suites and Robotics in Bariatric Surgery. In Surgical Management of Obesity. Editors, Buchwald H, Cowan GSM, Pories WJ. Elsevier Science, Philadelphia. pp 441-446.2007.

17. Narula VK and Melvin WS. Laparoscopic Adrenalectomy. In Current Surgical Therapy, 9^th edition. Editor, Cameron JL. Elsevier Science, 2007.

18. Narula VK and Melvin WS. Robotic Surgical Systems. In Robotic Urology Surgery. Editor, Vipul Patel. Springer-Verlag, London, pp. 5-15, 2007.

19. Gould JG, Melvin WS., Advances and Controversies in Minimally Invasive Surgery. Guest Editor, Surgical Clinics of North America 88(5), 2008.

20. Melvin WS. Commentary on: Robotics in Bariatric Surgery. In Atlas of Bariatric and Metabolic Surgery. Editor, Daniel Jones. Cinemed, Waterbury, CT, USA. 2010.

21. Eakin J, Melvin WS. Management of Achalasia. In Current Surgical Therapy, 10^th edition. Editor, Cameron JL. Elsevier Science, 2010.

22. Perry KA, Melvin WS. Open repairs of Paraesophageal and Diaphragmatic Hernias. In Mastery of Surgery, 6^th edition. eds, Fischer JE, et al. Wolters and Kluwer, p 260-274. 2011

23. Demyttenaere S, Melvin WS. Laparoscopic Robotic Distal Pancreatectomy and Splenectomy. In American College of Surgeons Atlas of Surgery. Pancreas Surgery Volume, Eds Asbun HJ, Fuchshuber PR., American College of Surgeons, p 201-207, 2011.

24. Melvin WS. Minimally Invasive Approaches to Pancreatic Surgery. Evidenced based Approach to Minimally Invasive Surgery. Eds. Murayama KM, Chand B, Kothari SN, Mikami D, Nagle A. Cine-Med, 2012. pp.285-294.

25. Melvin WS. Endoluminal Treatment of Reflux, In Mastery of Surgery, 6^th Edition, ed., Fischer, J. pp 870-875. 2012.

26 Muscarella P, Melvin WS. Common Bile Duct Exploration. Up to Date, http://www.uptodate.com/contents/common-bile-duct-exploration ed. Ashley S. 2011.

27. Goldblatt MI, Melvin WS. Prevention and Management of Complications in
Minimally Invasive Esophageal Surgery. In Prevention and Management of Complications in Laparoendoscopic Surgery. 3rd ed. Editors, Wetter PA, Kavic MS, Levinson CJ and Kelley W. 2011.

28.Hazey JE, Melvin WS. Common Endoscopic Complication: Recognition and Management. IN The SAGES Manual of Quality Outcomes and Patient Safety. Eds. Tichanzky DS, Morton J, Jones DB. Springer, 207-22. 2011.

29. Renton DR, Melvin WS. Laparoscopic Cholecystectomy with and without Common Bile Duct Exploration, Master Techniques in General Surgery: Hepatobiliary and Pancreatic Surgery ed. Drs. Lillemoe and Jarnagin. Lipincott, William&Wilkins, Philadelphia. 2013, 161-172

30. Perry KA, Melvin WS. Endoscopic Antireflux Repair—EsophyX to the book Master Techniques in General Surgery: Foregut Surgery, ed. Luketich. Lippincott, William &Wilkins, pp. 109-120. 2015.

31. Eakin J, Melvin WS. Endoluminal Treatment of Gastroesophageal Reflux Disease. Principles of Flexible Endoscopy.Ed. Marks, J, Dunkin B. Springer, 2013, pp. 157-166.

32. Melvin WS, Funk L. The Minimally Invasive Approach to Gastroesophageal Reflux Disease. Operative Techniques in Surgery. Ed, Mulholland M. Wolters and Kluwer. pp201-212, 2015.

33. Wendling MR, Melvin WS. Endoluminal Approaches to Gastroesophageal Reflux Disease. Current Surgical Therapy, 11^th ed. Cameron JL. Elsevier Saunders, 2014. pp. 14-19.

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