Overview Nathan Shock Center of Excellence The NIA-supported Einstein Nathan Shock Center (E-NSC) represents a collection of nearly 80 internal and external faculty actively engaged in high-impact science and collaborations in the biology of aging, three innovative, state-of-the-art Research Resource Cores, and extensive opportunities for enrichment and training in aging research. The Nathan Shock Center is structured aroundfour research cores Proteostasis of Aging Protein quality control maintenance and homeostasis Director: Ana Maria Cuervo, M.D. Ph.D. Learn More Health Span Physiologic phenotyping through lifespan Director: Derek Huffman, Ph.D. Learn More Human Multi-omics Data Human high-throughput omics data sharing and technical advising Directors: Jan Vijg, Ph.D. and Nir Barzilai, M.D. Learn More Research Development Ensuring the future of Biology of Aging through mentoring, P&F funding, and education Director: Sofiya Milman, M.D. Learn More Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Publications See More Autophagy gene expression in skeletal muscle of older individuals is associated with physical performance, muscle volume and mitochondrial function in the study of muscle, mobility and aging (SOMMA) Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology Somatic mutations in aging and disease Plasma proteomic profile of abdominal obesity in older adults An iron rheostat controls hematopoietic stem cell fate