Overview Aging has a biology, and this biology drives age-related diseases (Geroscience). We at Einstein have demonstrated that the biology of aging can be targeted in experimental models to delay, stop, and in some examples, reverse manifestations of aging. Our overarching Mission is to make scientific discoveries in geroscience, leveraging on the expertise in our center in studying and targeting the pillars of aging, and to confirm their relevance of new findings to human aging through the unique Gero-human resource created in our center and to translate interventions proven relevant for human to drug discovery efforts. Centers of Excellence The institute for Aging Research is the home of two aging centers of international recognition. The Nathan Shock Center of Excellence, focused on the study of the biology of aging and the Einstein Paul F. Glenn Center solely dedicate to understanding the biology behind human Aging. Learn More Nathan Shock Center of Excellence LEARN MORE The Paul F. Glenn Center for Biology of Human Aging LEARN MORE Research Integrative Physiology Dietary strategies to delay aging Metabolism targeting to delay aging Cell autonomous and non-autonomous aging CNS control of metabolism and aging Cell Biology of Aging Proteostasis DNA repair Response to Stress Inflammaging Stem Cells Genetics of Aging Human Longevity Comparative genomics of longevity Translational Geroscience TAME Human Longevity Studies Clinical Geriatrics Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Multimedia 2nd Annual Longevity Studies Symposium More Videos Highlights News Release Einstein Aging Study Receives $32 Million Grant to Study Alzheimer’s Disease Apr 20, 2022 News Release Einstein Researchers Find New Strategy for Preventing Clogged Arteries Mar 28, 2022 News Release Promising Approach Against Treatment-Resistant Cancer Mar 07, 2022 See All Publications See More Biopolymeric nanoparticles based effective delivery of bioactive compounds toward the sustainable development of anticancerous therapeuticsTargeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degenerationClonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in HumansEvidence for preserved insulin responsiveness in the aging rat brainChaperone-mediated autophagy protects against atherosclerosisIntegrity of hypothalamic-pituitary-testicular axis in exceptional longevityBiochemical, dielectric and surface characteristics of freeze-dried bovine colostrum whey powderMethamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV NeuropathogenesisMisfolded GBA/β-glucocerebrosidase impairs ER-quality control by chaperone-mediated autophagy in Parkinson diseaseThe immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development